Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
The "Writing on the Wall Maneuver" Reveals the Dystonic Nature of Primary Writing Tremor. [PDF]
Mov Disord Clin PractErro R +4 more
europepmc +1 more source
Advanced Science, EarlyView.A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source
Understanding Church-Led Adolescent and Youth Sexual Reproductive Health (AYSRH) Interventions Within the Framework of Church Beliefs and Practices in South Africa: A Qualitative Study. [PDF]
Healthcare (Basel)Magezi V, Hoffman J, Leeson GW.
europepmc +1 more source
Real‐Time Ferroelectric Domain Wall Dynamics During Electric Poling and Depoling
Advanced Science, EarlyView.Real‐time visualization of domain wall dynamics during alternating‐current poling, direct‐current poling, and electrical depoling in relaxor‐PT ferroelectric single crystals reveals distinct field‐dependent pathways and strong path dependence. Instant polarized light microscopy uncovers reversible domain wall nucleation, motion, and reconfiguration ...
Ziqi Wang +12 more
wiley +1 more source
Is this Judaism? The Question of the Consistency of Israeli Policy and Actions in Gaza with Jewish Thought and Ethics : Part 1: Formulating the problem and methodological and hermeneutic considerations. [PDF]
J Bioeth InqKomesaroff PA, Kenner JZ.
europepmc +1 more source
SPICE‐Compatible Compact Modeling of Cuprate‐Based Memristors Across a Wide Temperature Range
Advanced Electronic Materials, EarlyView.A physics‐guided compact model for YBCO memristors is introduced, incorporating carrier trapping, field‐induced detrapping, and a differential balance equation to describe their switching dynamics. The model is compared with experiments and implemented in LTspice, allowing realistic circuit‐level simulations.
Thomas Günkel +6 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.A fully coupled FEM–HH model shows that ideally capacitive microelectrodes can achieve lower charge‐density thresholds than Faradaic contacts under current‐controlled stimulation. The advantage stems from the dynamics of surface current density on capacitive interfaces, which redirects current beneath adherent neurons.
Aleksandar Opančar +2 more
wiley +1 more source
Bridging the gap in clinical research training: a qualitative study of postgraduate medical students' perceptions of good clinical practice education. [PDF]
Med Educ OnlineXiaoyun W +7 more
europepmc +1 more source
Scan‐Path‐ and Initial‐State‐Dependent Superdomain Switching in (111)‐Oriented PZT
Advanced Electronic Materials, EarlyView.Scan trajectory and initial superdomain topology govern polarization switching in (111)‐oriented PZT. Automated AFM writing, pulsing experiments, and interferometric 3D‐PFM show that raster scans reproducibly stabilize ordered Type‐I stripe superdomains with constrained variant selection, whereas spiral trajectories generate frustrated mixed‐variant ...
Rama Vasudevan +11 more
wiley +1 more source