Results 251 to 260 of about 1,012,533 (359)

Iron Deficiency Impairs Dendritic Cell Development and Function, Compromising Host Anti‐Infection Capacity

open access: yesAdvanced Science, EarlyView.
Iron deficiency reduces monocyte dendritic cell progenitor (MDP) numbers by inhibiting migration and proliferation while promoting apoptosis, subsequently reducing downstream common dendritic cell precursors (CDP) and dendritic cell (DC). Impaired DCs enter the lungs via blood circulation, where reduced antigen presentation impairs T‐cell activation ...
Quanzhong Ren   +8 more
wiley   +1 more source

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

open access: yesAdvanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang   +6 more
wiley   +1 more source

Editorial: Male hypogonadism: need for reclassification? [PDF]

open access: yesFront Endocrinol (Lausanne)
Cannarella R, Quinton R, Calogero AE.
europepmc   +1 more source

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