Results 11 to 20 of about 6,396 (182)

Fast Biclustering by Dual Parameterization [PDF]

open access: yes, 2015
We study two clustering problems, Starforest Editing, the problem of adding and deleting edges to obtain a disjoint union of stars, and the generalization Bicluster Editing.
Drange, Pål Grønås   +3 more
core   +8 more sources

Differential co-expression framework to quantify goodness of biclusters and compare biclustering algorithms [PDF]

open access: yesAlgorithms for Molecular Biology, 2010
Background Biclustering is an important analysis procedure to understand the biological mechanisms from microarray gene expression data. Several algorithms have been proposed to identify biclusters, but very little effort was made to compare the ...
Karuturi R Krishna Murthy, Chia Burton
doaj   +3 more sources

RUBic: rapid unsupervised biclustering. [PDF]

open access: yesBMC Bioinformatics, 2023
AbstractBiclustering of biologically meaningful binary information is essential in many applications related to drug discovery, like protein–protein interactions and gene expressions. However, for robust performance in recently emerging large health datasets, it is important for new biclustering algorithms to be scalable and fast.
Sriwastava BK   +3 more
europepmc   +4 more sources

Convex Biclustering [PDF]

open access: yesBiometrics, 2016
SummaryIn the biclustering problem, we seek to simultaneously group observations and features. While biclustering has applications in a wide array of domains, ranging from text mining to collaborative filtering, the problem of identifying structure in high-dimensional genomic data motivates this work.
Chi, Eric C.   +2 more
openaire   +4 more sources

Biclustering via Semiparametric Bayesian Inference [PDF]

open access: yesBayesian Analysis, 2022
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Murua, Alejandro   +1 more
openaire   +3 more sources

A Bayesian hierarchical hidden Markov model for clustering and gene selection: Application to kidney cancer gene expression data. [PDF]

open access: yesBiom J
Abstract We introduce a Bayesian approach for biclustering that accounts for the prior functional dependence between genes using hidden Markov models (HMMs). We utilize biological knowledge gathered from gene ontologies and the hidden Markov structure to capture the potential coexpression of neighboring genes.
Chekouo T, Mukherjee H.
europepmc   +2 more sources

Biclustering with heterogeneous variance [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
In cancer research, as in all of medicine, it is important to classify patients into etiologically and therapeutically relevant subtypes to improve diagnosis and treatment. One way to do this is to use clustering methods to find subgroups of homogeneous individuals based on genetic profiles together with heuristic clinical analysis.
Chen, Guanhua   +2 more
openaire   +2 more sources

Identification of bicluster regions in a binary matrix and its applications. [PDF]

open access: yesPLoS ONE, 2013
Biclustering has emerged as an important approach to the analysis of large-scale datasets. A biclustering technique identifies a subset of rows that exhibit similar patterns on a subset of columns in a data matrix.
Hung-Chia Chen   +3 more
doaj   +1 more source

Profile likelihood biclustering

open access: yesElectronic Journal of Statistics, 2020
Biclustering, the process of simultaneously clustering the rows and columns of a data matrix, is a popular and effective tool for finding structure in a high-dimensional dataset. Many biclustering procedures appear to work well in practice, but most do not have associated consistency guarantees.
Flynn, Cheryl, Perry, Patrick
openaire   +3 more sources

Ensemble Neighborhood Search (ENS) for biclustering of gene expression microarray data and single cell RNA sequencing data

open access: yesJournal of King Saud University: Computer and Information Sciences, 2022
Background: Ensemble biclustering comprises a class of biclustering algorithms that generates a consensus, better-quality partition/s as output. This concept has emerged from the fusion of existing biclustering methods hybridized upon selected aspects ...
Bhawani Sankar Biswal   +2 more
doaj   +1 more source

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