Including Aortic Valve Morphology in Computational Fluid Dynamics Simulations: Initial Findings and Application to Aortic Coarctation [PDF]
Computational fluid dynamics (CFD) simulations quantifying thoracic aortic flow patterns have not included disturbances from the aortic valve (AoV). 80% of patients with aortic coarctation (CoA) have a bicuspid aortic valve (BAV) which may cause adverse ...
Cava, Joseph Richard+8 more
core +2 more sources
Bicuspid Aortic Valve Disease [PDF]
Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media.
Siu, Samuel C., Silversides, Candice K.
openaire +4 more sources
Importance Transcatheter aortic valve replacement (TAVR) indications are expanding, leading to an increasing number of patients with bicuspid aortic stenosis undergoing TAVR.
R. Makkar+16 more
semanticscholar +1 more source
A comparison of the diagnostic capabilities of the ratio of acceleration time to total left ventricular ejection time (AT/ET) in determining the severity of aortic stenosis in patients with bicuspid and tricuspid aortic valve: retrospective comparative study [PDF]
Objective. We aimed to compare the diagnostic capabilities of the ratio of acceleration time to total left ventricular ejection time (AT/ET) in determining the severity of aortic stenosis (AS) in patients with bicuspid and tricuspid aortic valves (AV).
Vladlen V. Bazylev+4 more
doaj +1 more source
Turner syndrome and associated problems in turkish children: A multicenter study [PDF]
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls.
Abacı, A.+73 more
core +1 more source
Transcatheter Aortic Valve Replacement in Low-risk Patients With Bicuspid Aortic Valve Stenosis.
Importance The outcomes of transcatheter aortic valve replacement (TAVR) in low-risk patients with bicuspid aortic valve stenosis have not been studied in a large scale, multicentered, prospective fashion.
J. Forrest+12 more
semanticscholar +1 more source
Update in Biomolecular and Genetic Bases of Bicuspid Aortopathy
Bicuspid aortic valve (BAV) associated with aortopathy is the most common congenital heart disease in the general population. Far from being a simple harmless valve malformation, it can be a complex and heterogeneous disease and a source of chronic and ...
Alejandro Junco-Vicente+3 more
semanticscholar +1 more source
Aortic Coarctation: Recent Developments in Experimental and Computational Methods to Assess Treatments for this Simple Condition [PDF]
Coarctation of the aorta (CoA) is often considered a relatively simple disease, but long-term outcomes suggest otherwise as life expectancies are decades less than in the average population and substantial morbidity often exists.
Feinstein, Jeffrey A.+2 more
core +2 more sources
Association of recurrent fever and anemia with infective endocarditis in a 13-year-old girl with bicuspid aortic valve [PDF]
Introduction. Infective endocarditis is relatively rare in pediatric population, but can result in significant morbidity and mortality. Children with bicuspid aortic valve are at higher risk of developing infective endocarditis as compared to the general
Petrović Vesna+2 more
doaj +1 more source
Biological niches within human calcified aortic valves. Towards understanding of the pathological biomineralization process [PDF]
Despite recent advances, mineralization site, its microarchitecture, and composition in calcific heart valve remain poorly understood. A multiscale investigation, using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ...
Cavarretta, Elena+6 more
core +3 more sources