Results 61 to 70 of about 18,634 (215)

Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy

Frontiers in Cardiovascular Medicine, 2022
Bicuspid aortic valve (BAV), which affects up to 2% of the general population, results from the abnormal fusion of the cusps of the aortic valve. Patients with BAV are at a higher risk for developing aortic dilatation, a condition known as bicuspid ...
Ali Fatehi Hassanabad, Melissa A. King, Elena Di Martino, Elena Di Martino, Elena Di Martino, Paul W. M. Fedak, Julio Garcia, Julio Garcia, Julio Garcia, Julio Garcia   +9 more
doaj   +1 more source

Long‐Term Durability of Transcatheter Aortic Valves in Patients With Bicuspid Aortic Stenosis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Data concerning the long‐term durability of transcatheter aortic valves (TAVs) in patients with bicuspid aortic stenosis (AS) are lacking. Aims The study aims to report data on long‐term valve durability following transcatheter aortic valve replacement (TAVR) in bicuspid AS.
Yuheng Jia, Annette Maznyczka, Mauro Boiago, Arif Khokhar, Daijiro Tomii, Antoinette Neylon, Pauline Danthine, Thomas Levesque, Paul Bamford, Stefan Toggweiler, Federico Moccetti, Jarkko Piuhola, Marianna Adamo, Mauro Massussi, Alfonso lelasi, Matteo Montorfano, Giulia Costa, Martin Swaans, Daniël C. Overduin, Clément Servoz, Caterina Gandolfo, Ingibjörg Jóna Guðmundsdóttir, Stefano Salizzoni, Joanna J. Wykrzykowska, Kees H. van Bergeijk, Andrea Buono, Tau Hartikainen, Stephane Noble, Darren Mylotte, Stephen Brecker, Ahmed Thabit, Antonio Mangieri, Pierfrancesco Agostoni, Matjaž Bunc, Maarten Vanhaverbeke, Johan Bosmans, Hélène Eltchaninoff, Azeem Latib, Daniel Blackman, Nicolas M. Van Mieghem, Yuan Feng, Won‐Keun Kim, Thomas Pilgrim, Bernard Prendergast, Didier Tchétché, Mao Chen, Ole De Backer   +46 more
wiley   +1 more source

Abnormal Haemodynamic Flow Patterns in Bicuspid Pulmonary Valve Disease

Frontiers in Physiology, 2017
Abnormal flow patterns in the aortas of those with bicuspid aortic valves (BAVs) are increasingly recognized as important in the pathogenesis of aortic dilatation but pulmonary flow patterns in bicuspid pulmonary valves have not been studied.
Malenka M. Bissell, Margaret Loudon, Stefan Neubauer, Saul G. Myerson   +3 more
doaj   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Valve-preserving surgery on the bicuspid aortic valve [PDF]

European Journal of Cardio-Thoracic Surgery, 2013
Valve repair has emerged as an important intervention for the management of bicuspid aortic valve disease. This systematic review aims to assess the safety, efficacy and durability of bicuspid aortic valve repair. Initial searches yielded 682 abstracts, reduced by de-duplication to 370, of which 56 full papers were accessed and 30 met the inclusion ...
Vohra, Hunaid, Whistance, Robert N, de Kerchove, Laurent, Punjabi, Prakash, El Khoury, Gebrine   +4 more
openaire   +4 more sources

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Reconstruction of the Bicuspid Aortic Valve [PDF]

Operative Techniques in Thoracic and Cardiovascular Surgery, 2007
Abicuspid aortic valve (BAV) occurs in 2% of the population and is a common reason for significant aortic regurgitation, particularly in the third and fourth decades of life.1 In these young patients, the choice of valve substitute is difficult. With a mechanical valve, the linearized risk of thromboembolic complications and anticoagulation-related ...
openaire   +2 more sources

Bicuspid Aortic Valve Disease: A Comprehensive Review

Cardiology Research and Practice, 2012
Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease.
Ify Mordi, Nikolaos Tzemos
doaj   +1 more source

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation

iMeta, EarlyView.
Multi‐omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)‐derived butyric acid (BA) as a key metabolite in the restoration of valve function in calcific aortic valve disease (CAVD). The therapeutic efficacy of BA in attenuating CAVD progression was confirmed in vitro, ex vivo, and in
Chunli Wang, Zongtao Liu, Tingwen Zhou, Jiaqin Wu, Fan Feng, Shunshun Wang, Qingjia Chi, Yongqiang Sha, Shuai Zha, Songren Shu, Linghang Qu, Qianqian Du, Huiming Yu, Li Yang, Anna Malashicheva, Nianguo Dong, Fei Xie, Guixue Wang, Kang Xu   +18 more
wiley   +1 more source

Recurrent infective endocarditis involving bicuspid aortic valve presenting with a rare complication: The deadly kiss

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2018
Bicuspid aortic valve, the most common congenital cardiac lesion, is frequently associated with infective endocarditis (IE), and this combination is notoriously associated with increased prevalence of periannular complications.
Arnab Ghosh Chaudhury, Prabhavathi Bhat, C N Manjunath, C M Satvic   +3 more
doaj   +1 more source