Results 11 to 20 of about 3,128 (180)

Design, Synthesis, and Structural Evolution of Pseudo-Natural Product IDO1 Inhibitors and Degraders. [PDF]

Angew Chem Int Ed Engl
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Cheng XF, Lucas B, Lampe P, Ugel S, Chen S, Unger A, Bischoff M, Adariani SR, Naredla KR, Kumar K, Schmidt A, Strohmann C, Janning P, Gasper R, Lucas M, Gersch M, Sievers S, Bronte V, Ziegler S, Waldmann H.   +19 more
europepmc   +3 more sources

Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities. [PDF]

Chem Biodivers
This review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
Castro JWG, Souza GGO, da Costa JGM, Rodrigues FFG.   +3 more
europepmc   +2 more sources

Evolving a generalist biosensor for bicyclic monoterpenes [PDF]

ACS Synthetic Biology, 2021
ABSTRACTProkaryotic transcription factors can be repurposed as analytical and synthetic tools for precise chemical measurement and regulation. Monoterpenes encompass a broad chemical family that are commercially valuable as flavors, cosmetics, and fragrances, but have proven difficult to measure, especially in cells.
Simon d’Oelsnitz, Vylan Nguyen, Hal S. Alper, Andrew D. Ellington   +3 more
openaire   +2 more sources

Synthesis and Biological Evaluation of Novel Pyrimidine Amine Derivatives Bearing Bicyclic Monoterpene Moieties

Molecules, 2022
A series of novel pinanyl pyrimidine amine derivatives (1e~1n) and camphoryl pyrimidine amine derivatives (2b~2f) bearing bicyclic monoterpene moieties were designed and synthesized from natural and renewable nopinone and camphor. All chemical structures of target compounds were characterized by 1H NMR, 13C NMR and HRMS spectra analyses, and the ...
Mingguang Zhang, Yunyun Wang, Shifa Wang, Hongyan Wu   +3 more
openaire   +3 more sources

Borneol, a Bicyclic Monoterpene Alcohol, Reduces Nociceptive Behavior and Inflammatory Response in Mice [PDF]

The Scientific World Journal, 2013
Borneol, a bicyclic monoterpene, has been evaluated for antinociceptive and anti‐inflammatory activities. Antinociceptive and anti‐inflammatory activities were studied by measuring nociception by acetic acid, formalin, hot plate, and grip strength tests, while inflammation was prompted by carrageenan‐induced peritonitis.
Jackson Roberto Guedes da Silva Almeida, Grasielly Rocha Souza, Juliane Cabral Silva, Sarah Raquel Gomes de Lima Saraiva, Raimundo Gonçalves de Oliveira Júnior, Jullyana de Souza Siqueira Quintans, Rosana de Souza Siqueira Barreto, Leonardo Rigoldi Bonjardim, Sócrates Cabral de Holanda Cavalcanti, Lucindo José Quintans Junior   +9 more
openaire   +3 more sources

The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen [PDF]

, 2014
BACKGROUND: The facultatively anaerobic betaproteobacterium Castellaniella defragrans 65Phen utilizes acyclic, monocyclic and bicyclic monoterpenes as sole carbon source under oxic as well as anoxic conditions.
Becher, D., Disch, E., Harder, J., Huettel, B., Markert, S., Petasch, J., Reinhardt, R., Schweder, T.   +7 more
core   +2 more sources

Chemical Composition of Leaf and Seed Oils of Dryobalanops aromatica Gaertn. (Dipterocarpaceae)

ASEAN Journal on Science and Technology for Development, 2012
The essential oils of the leaves and seed of Dryobalanops aromatica Gaertn. obtained by hydrodistillation resulted in 0.07% and 1.89% yield, respectively. These oils were then examined by GC-MS.
A.S Kamariyah, T Ozek, B Demirci, K.H.C. Baser   +3 more
doaj   +1 more source

Shared phytochemicals predict efficacy of essential oils against western flower thrips (Frankliniella occidentalis) in the greenhouse

Chemical and Biological Technologies in Agriculture, 2022
Western flower thrips (Frankliniella occidentalis; Thysanoptera: Thripidae), or WFT, are a global pest of commercial crops, particularly those grown in greenhouses. Current management recommendations often involve judicious use of pesticides to which WFT
Tiffany D. Durr, Chase A. Stratton, Noura S. Dosoky, Prabodh Satyal, Ebony G. Murrell   +4 more
doaj   +1 more source

Thioterpenoids as Potential Antithrombotic Drugs: Molecular Docking, Antiaggregant, Anticoagulant and Antioxidant Activities

Biomolecules, 2022
Natural monoterpenes and their derivatives are widely considered as effective ingredients for the design and production of new biologically active compounds with high antioxidant, antimicrobial and anti-protozoa properties.
Alexander A. Ksenofontov, Pavel S. Bocharov, Elena V. Antina, Oksana G. Shevchenko, Aleksandr V. Samorodov, Ilmir R. Gilfanov, Roman S. Pavelyev, Olga V. Ostolopovskaya, Valeriya A. Startseva, Inna V. Fedyunina, Zulfiya R. Azizova, Salavat I. Gaysin, Svetlana V. Pestova, Evgeniy S. Izmest’ev, Svetlana A. Rubtsova, Mohammed A. Khelkhal, Liliya E. Nikitina   +16 more
doaj   +1 more source

Update on Monoterpenes from Red Macroalgae: Isolation, Analysis, and Bioactivity

Marine Drugs, 2019
Macroalgae produce a wide range of monoterpenes as secondary metabolites of mevalonate (MVA) and/or methylerythritol phosphate (MEP) pathway (often including haloperoxidase action).
Ana-Marija Cikoš, Mladenka Jurin, Rozelindra Čož-Rakovac, Stela Jokić, Igor Jerković   +4 more
doaj   +1 more source