Results 31 to 40 of about 2,274 (258)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Relationship between Return and the Bid-Ask Spread in Tehran Stock Exchange [PDF]

open access: yesتحقیقات مالی, 2012
This paper studies the relationship between return and the Bid-Ask Spread in Tehran Stock Exchange. The research has been done according to Amihud and Mendelson’s model (1986).
Hasan Ghalibaf Asl, Mohadeseh Razaghi
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

PERUBAHAN BID ASK SPREAD DI SEPUTAR PENGUMUMAN LABA UNTUK SAHAM PERUSAHAAN MANUFAKTUR DI BURSA EFEK INDONESIA

open access: yesBenefit Jurnal Manajemen dan Bisnis, 2017
This study aimed to test whether there are significant non-financial variable to the bid ask spread around each earnings announcement on Manufacturing companies listed on the Indonesia Stock Exchange.
Bayu Wijayantini
doaj  

Investigating the effect of Trading volume on Bid-Ask spread of Islamic treasury bills with a Microstructural approach [PDF]

open access: yesIranian Journal of Finance
As a key tool in implementing monetary policy and government financing, government bonds play an essential role in financial markets. By means of Islamic financial innovations in the Islamic capital market, the instrument of Islamic treasury bill is ...
Ali Namaki, Aysa Kazemi bavil
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Bias in the effective bid-ask spread

open access: yesJournal of Financial Economics, 2021
Abstract The effective bid-ask spread measured relative to the spread midpoint overstates the true effective bid-ask spread in markets with discrete prices and elastic liquidity demand. The average bias is 13%–18% for S&P 500 stocks in general, depending on the estimator used as benchmark, and up to 97% for low-priced stocks.
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

PENGARUH HARGA SAHAM, VOLATILITAS HARGA SAHAM, DAN VOLUME PERDAGANGAN SAHAM TERHADAP BID-ASK SPREAD SAHAM PADA PERUSAHAAN SEKTOR PERTAMBANGAN YANG TERDAFTAR DI ISSI PERIODE JUNI 2016−JUNI 2017

open access: yesJurnal Riset Manajemen Sains Indonesia, 2018
Penelitian ini bertujuan untuk mengetahui pengaruh harga, volatilitas harga dan volume perdagangan saham terhadap bid-ask spread pada perusahaan sektor pertambangan yang terdaftar di Indeks Saham Syariah Indonesia (ISSI) periode Juni 2016 – Juni 2017 ...
Hamidah Hamidah   +2 more
doaj  

Does Demutualization Spur Liquidity?

open access: yesSEISENSE Journal of Management, 2020
Purpose: The literature on demutualization is confined to efficiency and social welfare issues. Little empirical literature exists on the effect of demutualization on listed firms.
Farman Ali   +3 more
doaj   +1 more source

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