Results 101 to 110 of about 2,953,844 (279)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Reliability Assessment of Research into Contractors’ Bidding Decisions
Procedia Engineering, 2015 AbstractThe most popular system for contracting construction works in the Polish market is the tender procedure. The selection of tenders in which a company will take part is very important as it plays a vital role in building its position on the market. Making a bid/no bid decision is influenced by a number of factors.
openaire +1 more source
Elicited Bid Functions in a (a)Symmetric First-Price Auctions [PDF]
We report on a series of experiments that examine bidding behavior in first-price sealed bid auctions with symmetric and asymmetric bidders.To study the extent of strategic behavior, we use an experimental design that elicits bidders complete bid ...
Sadrieh, A., Pezanis-Christou, P.
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Bid-Ask Spreads, Volume, and Volatility: Evidence from Livestock Markets [PDF]
Understanding the determinants of liquidity costs in agricultural futures markets is hampered by a need to use proxies for the bid-ask spread which are often biased, and by a failure to account for a jointly determined micro-market structure. We estimate
Frank, Julieta, Garcia, Philip
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Revista Ingeniería de Construcción, 2010 Ambas, la determinación de licitar y la determinación del precio a licitar son muy importantes para cada contratista. La importancia de estas determinaciones descansa en el hecho que, el éxito o fracaso del negocio contratista, depende de los resultados ...
Adnan Enshassi +2 more
doaj
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
REVISITING BID DESIGN ISSUES IN CONTINGENT VALUATION [PDF]
A uniform bid design from a predetermined uniform distribution is proposed as a practical and robust alternative to existing optimal or naïve bid designs.
Haab, Timothy C., Kim, Sooil
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source