Results 81 to 90 of about 443,162 (297)

Determining the optimal bid direction of a generation company using the gradient vector of the profit function in the network constraints of the electricity market

IET Generation, Transmission & Distribution
One of the primary challenges faced by generation companies (GenCos), which operate multiple generation units within the electricity market, is the determination of the optimal bid price for these units to maximize profit.
Mohammad Ebrahim Hajiabadi, Mahdi Samadi, Mohammad Hassan Nikkhah, Hossein Lotfi, Li Li   +4 more
doaj   +1 more source

On bid-price controls for network revenue management

Stochastic Systems, 2015
We consider a network revenue management problem and advance its dual formulation. The dual formulation reveals that the (optimal) shadow price of capacity forms a nonnegative martingale.
Bariş Ata, Mustafa Akan
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Bid Increments in Second-Price Sealed Bid Auctions [PDF]

This note concerns bidding in a hybrid first-price and second-price auction. The winning bidder sometimes pays his bid and sometimes pays an amount determined by the next highest bid.
Richard Cox
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

A note on reserve price commitments in the Vickrey auction [PDF]

This note provides a simple explanation why sellers rarely set optimal reserve prices in one-shot auctions. In a standard sealed-bid second-price auction, bidders with private values do not bid truthfully if the seller cannot commit to her announced ...
Beck, Jonathan, Glowicka, Ela
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Semiparametric Estimation in Models of First-Price, Sealed-Bid Auctions with Affiliation [PDF]

Within the affiliated private-values paradigm, we develop a tractable empirical model of equilibrium behaviour at first-price, sealed-bid auctions. The model is non-parametrically identified, but the rate of convergence in estimation is slow when the ...
Hubbard, Timothy P., Li, Tong, Paarsch, Harry J.   +2 more
core  

Risk-Aware Budget-Constrained Auto-Bidding under First-Price RTB: A Distributional Constrained Deep Reinforcement Learning Framework

Journal of Advanced Computing Systems
Real-time bidding (RTB) has become the dominant mechanism for programmatic display advertising, and the industry has migrated from second-price to first-price auctions. First-price auctions simplify settlement but fundamentally change the cost dynamics:
Hanqi Zhang
doaj   +1 more source