Results 51 to 60 of about 241,539 (269)

Managing Risk of Bidding in Display Advertising

open access: yes, 2017
In this paper, we deal with the uncertainty of bidding for display advertising. Similar to the financial market trading, real-time bidding (RTB) based display advertising employs an auction mechanism to automate the impression level media buying; and ...
Amin K.   +10 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Alternatives to peer review: novel approaches for research evaluation

open access: yesFrontiers in Computational Neuroscience, 2011
In this paper we review several novel approaches for research evaluation. We start with a brief overview of the peer review, its controversies, and metrics for assessing efficiency and overall quality of the peer review.
Aliaksandr eBirukou   +10 more
doaj   +1 more source

Smart Contracts-Based Demand Response Bidding Mechanism to Enhance the Load Aggregator Model in Thailand

open access: yesEnergies, 2023
In 2022, Thailand’s Demand Response (DR) business model was shifting from the Traditional Utility (TU) model to the Load Aggregator (LA) model in accordance with Thailand’s smart grid master plan.
Anchisa Pinyo, Athikom Bangviwat
doaj   +1 more source

Priority Auctions and Queue Disciplines that Depend on Processing Time [PDF]

open access: yes, 2004
Lecture on the first SFB/TR 15 meeting, Gummersbach, July, 18 - 20, 2004We analyze the allocation of priority in queues via simple bidding mechanisms. In our model, the stochastically arriving customers are privately informed about their own processing ...
Kittsteiner, Thomas, Moldovanu, Benny
core   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Combinatorial Auction-Based Mechanism for Task Offloading in Edge Computing

open access: yesJisuanji kexue yu tansuo, 2021
In the era of the Internet of everything, the rapid increase in data volume and computation demand has prompted the evolution of application deployment mode from cloud computing to edge computing in order to reduce bandwidth consumption and response ...
LI Yinghao, SONG Tian, YANG Yating
doaj   +1 more source

A novel bidding method for combined heat and power units in district heating systems

open access: yes, 2018
We propose a bidding method for the participation of combined heat and power (CHP) units in the day-ahead electricity market. More specifically, we consider a district heating system where heat can be produced by CHP units or heat-only units, e.g., gas ...
Andersen, Anders N.   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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