Results 41 to 50 of about 7,191 (313)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Deep reinforcement learning-driven bidding strategy for wind-storage systems in energy and frequency regulation markets

电力工程技术
In the power market environment, participation of wind-storage system in both the energy market and the frequency regulation market is essential to enhance economic efficiency and support grid frequency regulation and peak shaving.
Zhongping LI, Yue XIANG
doaj   +1 more source

An Expected Win Rate-Based Real Time Bidding Strategy for Branding Campaign by the Model-Free Reinforcement Learning Model

IEEE Access, 2020
The bidding strategy plays the most important role to help the Demand Side Platforms (DSPs) making bidding decisions on a large number of bid requests in Real Time Bidding (RTB) to satisfy the different objectives of campaigns under the lifetime and ...
Wen-Yueh Shih, Yi-Shu Lu, Hsiao-Ping Tsai, Jiun-Long Huang   +3 more
doaj   +1 more source

Bidding strategy for an energy storage facility [PDF]

2016 Power Systems Computation Conference (PSCC), 2016
This paper studies operation decisions of energy storage facilities in perfectly and imperfectly competitive markets. In a perfectly competitive market, the storage facility is operated to maximize the social welfare. However, in a imperfectly competitive market, the storage facility operates to maximize its profit, while the market operator aims at ...
Ehsan Nasrolahpour, Hamidreza Zareipour, William D. Rosehart, S. Jalal Kazempour   +3 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Understanding bidding strategies of intermittent renewables in negative price environments: A theoretical and empirical analysis

Advances in Applied Energy
Negative electricity prices have become increasingly prevalent with the growing penetration of intermittent renewable energy sources worldwide. Although it is widely thought that the negative prices are primarily driven by intermittent renewable energies,
Qinghu Tang, Hongye Guo, Daniel S. Kirschen, Chongqing Kang   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Auction-Based Single-Sided Bidding Electricity Market: An Alternative to the Bilateral Contractual Energy Trading Model in a Grid-Tied Microgrid

IEEE Access
An auction-based single-sided bidding energy transaction mechanism in a grid-connected microgrid (MG) using a multi-agent system allows for better profit sharing for all stakeholders.
Hirekeri Malleshappa Manjunatha, Garighatta Krishnaiah Purushothama, Yashwanth Nanjappa, Raghavendraprasad Deshpande   +3 more
doaj   +1 more source

Greedy bidding strategies for keyword auctions [PDF]

Proceedings of the 8th ACM conference on Electronic commerce, 2007
How should players bid in keyword auctions such as those used by Google, Yahoo! and MSN?allWe consider greedy bidding strategies for a repeated auction on a single keyword, where in each round, each player chooses some optimal bid for the next round, assuming that the other players merely repeat their previous bid. We study the revenue, convergence and
Matthew Cary, Aparna Das, Benjamin Edelman, Ioannis Giotis 0001, Kurtis Heimerl, Anna R. Karlin, Claire Mathieu, Michael Schwarz 0002   +7 more
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source