Results 31 to 40 of about 9,914 (264)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Bidirectional positive buck-boost converter

, 2008
In a positive buck-boost (PBB) converter, inductor current and capacitor voltage can be decoupled which may improve system stability. In fact for a specific level of capacitor voltage, the inductor current can be adjusted at different levels and can be ...
Firuz Zare, Zare, Firuz, Arash A. Boora, zare, F., Ledwich, G., A. Boora, Arash, Boora, Arash A., Ghosh, Arindam, Gerard Ledwich, Arindam Ghosh, Ledwich, Gerard F., Ledwich, Gerard, Boora, A.   +12 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Fully soft switched high step‐up/down bidirectional buck/boost converter with reduced switch voltage stress

IET Power Electronics, 2023
A fully soft switched high step‐up/down bidirectional converter is presented in this paper. The high voltage conversion ratio is achieved by a pair of coupled inductors along with a switched capacitor while all active switches operate at zero voltage ...
Mohsen Packnezhad, Pouria Talebi, Hosein Farzanehfard   +2 more
doaj   +1 more source

Conversor CC-CC buck+boost multinível bidirecional [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Elétrica, Florianópolis, 2013Este trabalho apresenta uma nova topologia de conversor cc-cc Buck+Boost bidirecional multinível ...
Costa, Levy Ferreira
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Research on the Bidirectional Converter Setting Scheme for Urban Rail Transit Traction Power Supply System

Chengshi guidao jiaotong yanjiu
ObjectiveBidirectional converter technology is an important direction in the application technology research of intelligent and green urban rail transit traction power supply. Due to the differences in external characteristics of bidirectio-nal converter
Lijun DAI, Lixin YANG, Yu ZHANG, Yilong CHEN, Yifei WANG, Minghua CHENG   +5 more
doaj   +1 more source

Conexão série-série de módulos CC-CC isolados [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2015Esta tese apresenta a associação de conversores CC-CC de duas portas conectados em série-série tanto na ...
Bottion, Antonio José Bento
core  

Bidirectional AC DC Converter for Regenerative Braking [PDF]

, 2012
In this paper, a bidirectional AC DC converter is analyzed. The converter applies a half bridge thyristor rectifier and a recuperating thyristor bridge instead of a braking resistor.
Kolar, Johann W., Nishida, Yasuyuki, Pejovic, Predrag   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source