Results 41 to 50 of about 65,907 (244)

Stochastic modeling of cargo transport by teams of molecular motors

, 2013
Many different types of cellular cargos are transported bidirectionally along microtubules by teams of molecular motors. The motion of this cargo-motors system has been experimentally characterized in vivo as processive with rather persistent ...
A. Kunwar, B. Trinczek, D.T. Gillespie, D.T. Gillespie, G. Steinberg, K. Döhner, M.A. Welte, M.A. Welte, M.J.I. Müller, N. Hirokawa, N. J. Carter, R. Mallik, S. Klein, S.P. Gross   +13 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Vortex-induced Vibration of a Flexible Free-hanging Circular Cantilever [PDF]

ITB Journal of Engineering Science, 2009
An experimental investigation on time-dependent motion of a flexible free-hanging circular cantilever subjected to uniform cross-flows has been carried out. The free-end condition cantilever has a 34.4 aspect ratio and a low mass ratio of about 1.24. The
R. W. Prastianto, K. Otsuka, Y. Ikeda
doaj  

Energy-Based Seismic Risk Evaluation of Tall Reinforced Concrete Building in Vancouver, BC, Canada, under Mw9 Megathrust Subduction Earthquakes and Aftershocks

Frontiers in Built Environment, 2017
This article presents a seismic performance evaluation framework for reinforced concrete (RC) buildings, comprising shear walls and gravity frames. The evaluation is undertaken within a performance-based earthquake engineering framework by considering ...
Solomon Tesfamariam, Katsuichiro Goda
doaj   +1 more source

Bidirectional recurrent learning of inverse dynamic models for robots with elastic joints: a real-time real-world implementation

Frontiers in Neurorobotics, 2023
Collaborative robots, or cobots, are designed to work alongside humans and to alleviate their physical burdens, such as lifting heavy objects or performing tedious tasks.
Brayan Valencia-Vidal, Brayan Valencia-Vidal, Eduardo Ros, Ignacio Abadía, Niceto R. Luque   +4 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

A Self-Propelled Linear Piezoelectric Micro-Actuator Inspired by the Movement Patterns of Aquatic Beetles

Micromachines
The locomotion mechanisms and structural characteristics of insects in nature offer new perspectives and solutions for designing miniature actuators.
Xinjie Wang, Gen Wang
doaj   +1 more source

Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

, 2015
Cells are strongly out-of-equilibrium systems driven by continuous energy supply. They carry out many vital functions requiring active transport of various ingredients and organelles, some being small, others being large.
Appert-Rolland, Cecile, Ebbinghaus, Maximilian, Santen, Ludger   +2 more
core   +3 more sources

Optical Weak Link between Two Spatially Separate Bose-Einstein Condensates [PDF]

, 2005
Two spatially separate Bose-Einstein condensates were prepared in an optical double-well potential. A bidirectional coupling between the two condensates was established by two pairs of Bragg beams which continuously outcoupled atoms in opposite ...
D. E. Pritchard, G.-B. Jo, M. Saba, P. W. Anderson, T. A. Pasquini, W. Ketterle, Y. Shin   +6 more
core   +2 more sources