Results 221 to 230 of about 113,681 (310)

Development of a Highly Effective Bifunctional Ligand 2E-C-NETA for Targeted Lu-177 Therapy: Synthesis, Radiolabeling, In Vitro Stability, and In Vivo Biodistribution. [PDF]

ChemMedChem
Chen Y, Lee Y, Kang CS, Ren S, Chen Y, Wang H, Bandara N, Rogers BE, Chong HS.   +8 more
europepmc   +1 more source

Redox‐Modulated σ‐Bond Reactivity in a Radical‐Anion Dimer

Angewandte Chemie, EarlyView.
A radialene‐based radical anion σ‐dimer comprising an elongated C‐C bond exhibits orthogonal stimuli responsiveness. Homolytic cleavage of the dimer to the radical state is triggered by mechanical strain and high temperature. Dimer scission is also achieved via oxidation, resulting in formation of neutral radialenes.
Sushil Ranjan Bhatta, Jonathan H. Gillen, Amaya T. Jayaweera, Fuead Hasan, Diana P. Merenkov, Hai Zhao, Sepideh Asgari, Arthur H. Winter, Christopher M. Bejger   +8 more
wiley   +1 more source

On-Resin Synthesis and Diversification of Macrocyclic Disulfide Bridge Peptidomimetics via Bifunctional 5-Iodo-1,4-Triazoles. [PDF]

J Org Chem
Malone MA, Shepperson OA, Simms JE, Reid AJ, Jamieson AG.   +4 more
europepmc   +1 more source

Hole‐Activated Lattice Oxygen Enables Pt‐Free Propane Dehydrogenation by Eliminating the Hydrogen Recombination Bottleneck

Angewandte Chemie, EarlyView.
Trace Mg doping into gallia–alumina generates hole‐type oxygen species that accelerate hydrogen recombination, eliminating the need for Pt promotion. The fully oxide‐based catalyst resists sintering under repeated regeneration, outperforming benchmark PtSn and CrOx catalysts with exceptional stability over 30 dehydrogenation–regeneration cycles ...
DongHwan Oh, Jaewoo Jeong, Susung Lee, Younghwan Park, Seunghyuck Chi, Yaejun Baik, Hyungjun Kim, Hyeyoung Shin, Minkee Choi   +8 more
wiley   +1 more source

Development of a novel immune infiltration-based gene signature to predict prognosis and immunotherapy response of a novel anti-PD-L1/TGF-β bifunctional fusion protein in recurrent cervical cancer. [PDF]

Hum Vaccin Immunother
Mao Y, Xing N, Sun W, Bao X, Liu X, Wu R, Peng J.   +6 more
europepmc   +1 more source

Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates

Angewandte Chemie, EarlyView.
An alkyne‐tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the Kennedy pathway, allowing CuAAC‐based visualization of PE and affinity capture of PE‐conjugated LC3, ubiquitin, and GPI‐anchored proteins.
Yuan‐Ting Cho, Cindy Y. Jao, Zijun Xia, Brittany M. White‐Mathieu, Adrian Salic, Jeremy M. Baskin   +5 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

Angewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley, Michael Rust, Moritz Wagner, Ida R. Hipfinger, Paul J. N. Böhm, Cora L. Dieterich, Christopher M. Field, Michael J. Page, Jeremy G. Owen, Robert A. Keyzers, Shinichi Sunagawa, Jörn Piel   +11 more
wiley   +1 more source

Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance. [PDF]

Chemistry
Dolcini L, Lavelli D, Dal Corso A, Pignataro L.   +3 more
europepmc   +1 more source

Heterobimetallic Janus Catalysts for the One‐Pot Synthesis of Polar‐Apolar Block Copolymers

Angewandte Chemie, EarlyView.
Heterobimetallic Janus catalysts act as bifunctional initiators, combining two distinct polymerisation mechanisms in one pot to deliver well‐defined apolar‐polar block copolymers. Combining Earth abundant Ti and Al catalysts for respective α‐olefin and lactone polymerisation, the orthogonal activity is enabled by unprecedented initiation from a Ti ...
Raju Chambenahalli, Gary S. Nichol, Jennifer A. Garden   +2 more
wiley   +1 more source

CoP/Co₂P heterostructures embedded in biomass-derived carbons as efficient electrocatalysts for hydrogen and oxygen evolution reactions. [PDF]

RSC Adv
Dieng A, Subrati A, Hagheh-Kavousi Z, Ndiaye NM, Holade Y, Gutierrez-Pineda E, Moya SE, Ngom BD.   +7 more
europepmc   +1 more source