Results 151 to 160 of about 556,712 (359)

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou   +18 more
wiley   +1 more source

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang   +5 more
wiley   +1 more source

Three‐Channel Electron Engineered Fe‐88A@CeO2/CDs Nanozyme with Enhanced Oxidase‐Like Activity for Efficient Biomimetic Catalysis

open access: yesAdvanced Science, EarlyView.
xx xx. Abstract Iron‐based metal‐organic framework (MOF) nanozymes have garnered considerable attention owing to a large specific surface area, adjustable porosity, large Fe‐O clusters, and unsaturated Fe sites. However, the sluggish charge‐transfer rate and restricted active sites of the nanozymes lead to poor enzyme‐like activity and further impede ...
Kai Liu   +9 more
wiley   +1 more source

A kinematically Bifurcated Metamaterial for Integrated Logic Operation and Computing

open access: yesAdvanced Science, EarlyView.
A family of 2n‐side kinematic polygonal modules with n decoupled inputs and 2n extreme configurations via kinematic bifurcation is proposed. It allows integrating seven basic logic gates on a quadrilateral module. Moreover, a minimized Parallel Computing Sum of Products function is developed, enabling all 2‐bit arithmetic (including division ...
Kaili Xi   +6 more
wiley   +1 more source

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