Results 41 to 50 of about 406,011 (306)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Resonant Bifurcations

Journal of Mathematical Analysis and Applications, 2000
We consider dynamical systems depending on one or more real parameters, and assuming that, for some ``critical'' value of the parameters, the eigenvalues of the linear part are resonant, we discuss the existence -- under suitable hypotheses -- of a general class of bifurcating solutions in correspondence to this resonance.
openaire   +2 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Mechanical Properties of Architected Polymer Lattice Materials: A Comparative Study of Additive Manufacturing and CAD Using FEM and µ‐CT

Advanced Functional Materials, EarlyView.
This study examines how pore shape and manufacturing‐induced deviations affect the mechanical properties of 3D‐printed lattice materials with constant porosity. Combining µ‐CT analysis, FEM, and compression testing, the authors show that structural imperfections reduce stiffness and strength, while bulk material inhomogeneities probably enhance ...
Oliver Walker, Thierry Roland, Damien Favier, Antoine Egele, Michael Heymann, Cosima Stubenrauch   +5 more
wiley   +1 more source

Possibility of Atherosclerosis in an Arterial Bifurcation Model

BioImpacts, 2011
Introduction: Arterial bifurcations are susceptible locations for formation of atherosclerotic plaques. In the present study, steady blood flow is investigated in a bifurcation model with a non-planar branch.
Omid Arjmandi-Tash, Seyed Esmail Razavi, Ramin Zanbouri   +2 more
doaj   +1 more source

Complex Dynamics on the Routes to Chaos in a Discrete Predator-Prey System with Crowley-Martin Type Functional Response

Discrete Dynamics in Nature and Society, 2018
We present in this paper an investigation on a discrete predator-prey system with Crowley-Martin type functional response to know its complex dynamics on the routes to chaos which are induced by bifurcations.
Huayong Zhang, Shengnan Ma, Tousheng Huang, Xuebing Cong, Zichun Gao, Feifan Zhang   +5 more
doaj   +1 more source

Tipping points near a delayed saddle node bifurcation with periodic forcing

, 2015
We consider the effect on tipping from an additive periodic forcing in a canonical model with a saddle node bifurcation and a slowly varying bifurcation parameter.
Erneux, Thomas, Kuske, Rachel, Zhu, Jielin   +2 more
core   +1 more source

Fermi Surface Nesting and Anomalous Hall Effect in Magnetically Frustrated Mn2PdIn

Advanced Functional Materials, EarlyView.
Mn2PdIn, a frustrated inverse Heusler alloy, showing electronic‐structure driven anomalous Hall effect with Weyl crossings, Fermi‐surface nesting and near‐zero magnetization ideal for low‐magnetization spintronics. Abstract Noncollinear magnets with near‐zero net magnetization and nontrivial bulk electronic topology hold significant promise for ...
Afsar Ahmed, Arnab Bhattacharya, Prashant Singh, Ajay Kumar, Tukai Singha, Anis Biswas, Yaroslav Mudryk, I. Das   +7 more
wiley   +1 more source

Coarse Stability and Bifurcation Analysis Using Stochastic Simulators: Kinetic Monte Carlo Examples

, 2001
We implement a computer-assisted approach that, under appropriate conditions, allows the bifurcation analysis of the coarse dynamic behavior of microscopic simulators without requiring the explicit derivation of closed macroscopic equations for this ...
Kevrekidis, Ioannis G., Makeev, Alexei G., Maroudas, Dimitrios   +2 more
core   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

Advanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore, Cristiano Pesce, Antonietta Greco, Claudia Pisante, Greta Avancini, Valentina Di Francesco, Yosi Shamay, Paolo Decuzzi   +7 more
wiley   +1 more source