Results 201 to 210 of about 15,425 (247)

Dynamic complexity of Stackelberg-Bertrand game with one-way R&D spillovers, effective information and government subsidies. [PDF]

PLoS One
Long J, Zheng S.
europepmc   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Sparse identification of nonlinear dynamics applied to the acoustic levitation of acoustically large objects. [PDF]

Sci Rep
Akbarzadeh M, Halkon B, Oberst S.
europepmc   +1 more source

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

Cell Proliferation, EarlyView.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang, Yilong Zhao, Jiaru Deng, Shuyuan Qu, Yiyi Zhou, Qin Zhao, Yufeng Zhang   +6 more
wiley   +1 more source

Depolarization block induction via slow Na_V1.1 inactivation in Dravet syndrome. [PDF]

Sci Rep
Lemaire L, Desroches M, Rodrigues S, Campillo F.   +3 more
europepmc   +1 more source

Experiences of Legal Pluralism in Sierra Leone: Land Governance, Neoliberal Dispossession and Gender (In)justice

Development and Change, EarlyView.
ABSTRACT Sierra Leone's land governance reform policies are often based on the neoliberal assumption that market growth, gender equality and women's empowerment are mutually compatible objectives. Contrary to this assumption, this article argues that while market‐oriented reforms can help to destabilize legal and cultural norms that are discriminatory ...
Mohamed Sesay, Simeon Koroma
wiley   +1 more source

HIV/AIDS compartmental model analysis with drug resistance treatment, vertical transmission, and optimal control theory. [PDF]

Sci Rep
Peter OJ, Teklu SW, Balogun GB, Bolarin G, Asfaw MD.   +4 more
europepmc   +1 more source

Trust and fairness in platform–supplier contracts: Navigating supplier concerns in the sharing economy

Decision Sciences, EarlyView.
Abstract Trust and fairness are critical to the sustainable development of the sharing economy, particularly in platform–supplier relationships, where numerous individual suppliers offer access to their durable assets without transferring ownership. Motivated by the real‐world phenomenon of personalized wages and informed through direct interactions ...
Ying Yin, Xishu Li
wiley   +1 more source

Inspection of stability of a general roll-damping of a ship via non-perturbative approach. [PDF]

Sci Rep
Moatimid GM, Mohamed MAA, Abohamer MK.
europepmc   +1 more source

Therapeutic potential of mesenchymal stem cells in peripheral nerve injuries in horses

Equine Veterinary Education, EarlyView.
Summary Peripheral nerve injuries (PNI) in horses represent a significant clinical challenge, frequently associated with functional deficits and reduced athletic performance. Conventional therapeutic approaches, primarily based on anti‐inflammatory treatments and rehabilitation, offer limited efficacy, driving the search for innovative alternatives. In
L. V. de Oliveira Ferreira, R. Martins Amorim   +1 more
wiley   +1 more source