Results 71 to 80 of about 152,071 (342)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

The Modelling and Control of a Singular Biological Economic System in a Polluted Environment

Discrete Dynamics in Nature and Society, 2016
A singular biological economic model with harvesting and stage structure is presented. The local stability of equilibriums of the system is investigated when the economic profit parameter is zero, and the conditions of the singularity induced bifurcation
Yi Zhang, Yueming Jie, Xinyou Meng
doaj   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

Advanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger, Paolo Cardone, Charlotte Martial, Yonatan Sanz Perl, Iván Mindlin, Jacobo D Sitt, Leor Roseman, Robin Carhart‐Harris, David Nutt, Pablo Mallaroni, Natasha Mason, Johannes G Ramaekers, Vincent Bonhomme, Steven Laureys, Gustavo Deco, Olivia Gosseries, Pablo Núñez, Jitka Annen   +17 more
wiley   +1 more source

Global Hopf bifurcation for differential-algebraic equations with state dependent delay

, 2017
We develop a global Hopf bifurcation theory for differential equations with a state-dependent delay governed by an algebraic equation, using the $S^1$-equivariant degree.
Hu, Qingwen
core   +1 more source

Periodic orbits for an autonomous version of the Duffing–Holmes oscillator

Nonlinear Analysis
In the autonomous Duffing–Holmes oscillator, the existence of periodic orbits was detected numerically. Using the Hopf bifurcation theory, we prove analytically that such periodic orbits exist.
Guangfeng Dong, Jaume Llibre
doaj   +1 more source

Numerical bifurcation and hybrid control of a Gompertz model with time delay

Journal of Hebei University of Science and Technology, 2019
In order to study the stability of species, the biological systems are required to reduce or expand the stable region. For a Gompertz model with time delay, a hybrid control Euler method is proposed in which state feedback and parameter perturbation are ...
Jizhi SONG, Yuanyuan WANG
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Uniform approximations for non-generic bifurcation scenatios including bifurcations of ghost orbits

, 1999
Gutzwiller's trace formula allows interpreting the density of states of a classically chaotic quantum system in terms of classical periodic orbits. It diverges when periodic orbits undergo bifurcations, and must be replaced with a uniform approximation ...
Arnold, Arnold, Artuso, Bartsch, Birkhoff, Cvitanović, Einstein, Feynman, Friedrich, G. Wunner, Goldstein, Gustavson, Gutzwiller, Gutzwiller, Gutzwiller, Gutzwiller, Gutzwiller, Hasegawa, J. Main, Kuś, Main, Main, Main, Mao, Meyer, Ozorio de Almeida, Ozorio de Almeida, Peters, Poston, Sadovskiı́, Sadovskiı́, Schomerus, Schomerus, Schomerus, Schomerus, Schulman, Sieber, Sieber, Sirovich, T. Bartsch, Watanabe, Wintgen   +41 more
core   +2 more sources

Frequency bifurcation in a series-series compensated fractional-order inductive power transfer system

Journal of Advanced Research, 2020
This paper reveals and analyzes the frequency bifurcation phenomena in the fractional-order inductive power transfer (FOIPT) system with series-series compensation topology.
Xujian Shu, Bo Zhang, Chao Rong, Yanwei Jiang   +3 more
doaj   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source