Results 31 to 40 of about 54,758 (206)

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Multi-site breathers in Klein-Gordon lattices: stability, resonances, and bifurcations

, 2013
We prove the most general theorem about spectral stability of multi-site breathers in the discrete Klein-Gordon equation with a small coupling constant.
Anton Sakovich, Bambusi D, Broer H, Dmitry Pelinovsky, James G, Kato T, Koukouloyannis V, MacKay R S, Simo C, Yakubovich V A, Yoshimura K, Zeidler E   +11 more
core   +1 more source

Symmetric bifurcation analysis of synchronous states of time-delayed coupled Phase-Locked Loop oscillators [PDF]

, 2014
In recent years there has been an increasing interest in studying time-delayed coupled networks of oscillators since these occur in many real life applications.
Correa, Diego Paolo Ferruzzo, Piqueira, Jose Roberto Castilho, Wulff, Claudia   +2 more
core   +2 more sources

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Universality in Systems with Power-Law Memory and Fractional Dynamics

, 2017
There are a few different ways to extend regular nonlinear dynamical systems by introducing power-law memory or considering fractional differential/difference equations instead of integer ones.
A Toib, AA Kilbas, AA Kilbas, AA Kilbas, BN Lundstrom, BN Lundstrom, C Pozzorini, D Baleanu, D Matignon, D Mozyrska, D Mozyrska, D Mozyrska, DA Leopold, DC Rubin, F Atici, G-C Wu, G-C Wu, GA Anastassiou, GM Zaslavsky, GSF Frederico, HL Gray, I Petras, I Podlubny, JT Wixted, JT Wixted, JT Wixted, KS Miller, M Edelman, M Edelman, M Edelman, M Edelman, M Edelman, M Rivero, M Wyrwas, MJ Kahana, MS Zilany, N Ulanovsky, NRO Bastos, NRO Bastos, P Cvitanovic, RAC Ferreira, RM May, SG Samko, VE Tarasov, VE Tarasov, VE Tarasov   +45 more
core   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Hamiltonian thermodynamics of the Reissner-Nordstr\"om-anti-de Sitter black hole

, 1996
We consider the Hamiltonian dynamics and thermodynamics of spherically symmetric Einstein-Maxwell spacetimes with a negative cosmological constant. We impose boundary conditions that enforce every classical solution to be an exterior region of a Reissner-
A. Ashtekar, A. Ashtekar, B. Carter, B. Carter, B. F. Whiting, B. F. Whiting, B. Hoffmann, C. J. Isham, C. O. Lousto, C. O. Lousto, C. O. Lousto, C. W. Misner, D. Garfinkle, D. Kramer, D. Louis-Martinez, D. Marolf, D. N. Page, D. N. Page, G. L. Comer, G. W. Gibbons, G. W. Gibbons, H. W. Braden, H. W. Braden, J. B. Hartle, J. D. Bekenstein, J. D. Bekenstein, J. D. Brown, J. D. Brown, J. D. Brown, J. D. Brown, J. D. Brown, J. Gegenberg, J. Gegenberg, J. Louko, J. Louko, J. Melmed, J. W. York, K. Lake, K. V. Kuchař, L. E. Reichl, L. Smolin, M. Bañados, M. Henneaux, M. Henneaux, M. Reed, M. Varadarajan, N. M. J. Woodhouse, O. B. Zaslavskii, P. C. W. Davies, P. C. W. Davies, P. Kraus, R. D. Sorkin, R. M. Wald, S. Bose, S. Carlip, S. Carlip, S. R. Lau, S. W. Hawking, S. W. Hawking, S. W. Hawking, S. W. Hawking, T. Thiemann, T. Thiemann, W. G. Unruh, W. Israel   +64 more
core   +1 more source

DC‐magnetometry Analytical Tool Driven by Spin Ordering Phenomena for Sensing Chemical Interactions at the Surface of Nanomaterials

Advanced Science, EarlyView.
The adsorption of AsV on akaganeite nanorods was found to provide a magnetic signature. A change in the surface spin order gave rise to a second peak in the zero‐field cooled curve. AsIII adsorption does not provide any change in the magnetic behavior of the sorbent.
Marco Sanna Angotzi, Valentina Mameli, Alessandra Fantasia, Cesare Atzori, Giovanni Bertoni, Vincenzo Grillo, Giorgio Divitini, Dominika Zakutna, Jana Vejpravova, Martin Kalbac, Jan Plšek, Carla Cannas   +11 more
wiley   +1 more source