Results 201 to 210 of about 24,640,092 (292)

Exploring the role of place visitation big data on small area health measure estimation. [PDF]

Comput Urban Sci
Akinboyewa T, Ning H, Li Z, Lessani MN, Li X, Qiao S.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Thicket of Diversity Pamphlet

Fundraising pamphlet for the Big Thicket Association's "Thicket of Diversity" All Taxa Biodiversity Inventory of Big Thicket National Preserve projectThe Big Thicket Collection contains materials relating to the conservation of the Big Thicket area of ...
Big Thicket Association
core  

Big Data and Trustworthy AI for Heart Failure: A Review. [PDF]

Circ Heart Fail
Perramon-Llussà J, Skorupko G, Rao S, Ruiz Pujadas E, Jouide El Kaderi S, Stepin I, Mamouei M, Boonstra M, Triantafyllidis A, Asselbergs FW, Salimi-Khorshidi G, Lekadir K, Gkontra P.   +12 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Correction to: Sampling for computational efficiency when conducting analyses in big data. [PDF]

Am J Epidemiol
europepmc   +1 more source

The adaptive immune receptors in a big data world. [PDF]

Immunohorizons
DeKosky BJ.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

From the Guest Editors: Artificial Intelligence and Big Data in the Health Sciences. [PDF]

Dela J Public Health
Shi W, Deng Y.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source