Results 251 to 260 of about 724,460 (303)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Big Data for Drug Discovery: Some Historical Landscape, Considerations, and Applications for a Medicinal Chemist. [PDF]

ACS Omega
de Lima JAL, Silva Franco L, Lima LM.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Wearable sensor big data analysis reveals spatiotemporal injury patterns in professional tennis players. [PDF]

Sci Rep
Han G, Zhang Y, Sun B.
europepmc   +1 more source

BIG DATA Data Driven Agronomy Community of Practice – Work Plan 2018

, 2019
CGIAR Platform for Big Data in Agriculture
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Construction of a Big Data-Driven Predictive Analysis Platform for Hospital Talent Attrition. [PDF]

Blockchain Healthc Today
Zheng XL, Dai X, Liu TL.
europepmc   +1 more source

Rise of Big Data in Spine Surgery Research: A Bibliometric Analysis, 1993-2024. [PDF]

Cureus
Gerstmeyer J, Gorbacheva A, Pierre C, Von Glinski A, Heffernan T, Jouppi L, Godolias P, Schildhauer TA, Abdul-Jabbar A, Oskouian RJ, Chapman J.   +10 more
europepmc   +1 more source

Lightweight Structural Design of UAM Fuselage Using AI Predictive Modeling and Composite Big Data from Automated Manufacturing. [PDF]

Materials (Basel)
Son WH, Kim JH, Bae SY.
europepmc   +1 more source

Correction: NanoBERTa-ASP: predicting nanobody paratope based on a pretrained RoBERTa model

BMC Bioinformatics
Shangru Li, Xiangpeng Meng, Rui Li, Bingding Huang, Xin Wang   +4 more
doaj   +1 more source