Results 281 to 290 of about 3,434,319 (342)

Antithrombotic treatment of cervical arterial dissection: Big data needed to inform long-term management. [PDF]

Eur Stroke J
Ornello R, Foschi M.
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Correction: NanoBERTa-ASP: predicting nanobody paratope based on a pretrained RoBERTa model

BMC Bioinformatics
Shangru Li, Xiangpeng Meng, Rui Li, Bingding Huang, Xin Wang   +4 more
doaj   +1 more source

Enabling pan-repository reanalysis for big data science of public metabolomics data. [PDF]

Nat Commun
El Abiead Y, Strobel M, Payne T, Fahy E, O'Donovan C, Subramamiam S, Vizcaíno JA, Yurekten O, Deleray V, Zuffa S, Xing S, Mannochio-Russo H, Mohanty I, Zhao HN, Caraballo-Rodriguez AM, P Gomes PW, Avalon NE, Northen TR, Bowen BP, Louie KB, Dorrestein PC, Wang M.   +21 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

How big data analytics improves hospital environmental performance through supply chain innovation, decision quality, and risk taking. [PDF]

Sci Rep
Xinqi L, Xinghai Y, Shengyao Y, Jenatabadi HS, Samsudin N.   +4 more
europepmc   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Big data analytics in food industry: a state-of-the-art literature review. [PDF]

NPJ Sci Food
Siddique A, Gupta A, Sawyer JT, Huang TS, Morey A.   +4 more
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source