Results 201 to 210 of about 24,236,404 (304)

Hybrid Synthetic Minority Over-sampling Technique (HSMOTE) and Ensemble Deep Dynamic Classifier Model (EDDCM) for big data analytics. [PDF]

Sci Rep
M P, Tyagi B, R NP, B M.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Big data analytics and AI as success factors for online video streaming platforms. [PDF]

Front Big Data
Arshad M, Onn CW, Ahmad A, Mogwe G.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

RETRACTION: Challenges and Opportunities of Big Data Analytics in Healthcare. [PDF]

Health Care Sci
europepmc   +1 more source

Cultivating competitive advantage for Chinese SMEs via big data analytics: The mediating role of data-driven innovation and antecedents of data governance and data-driven culture. [PDF]

PLoS One
Rixin S, Ramayah, Xinrui M.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Reimagining Resilience in Aging: Leveraging AI/ML, Big Data Analytics, and Systems Innovation. [PDF]

Am J Geriatr Psychiatry
Chen J, Maguire TK, McCoy RG, Thomas S, Reynolds CF.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A novel approach in diagnosing knee osteoarthritis for content based image retrieval in big data analytics and medical images. [PDF]

Sci Rep
Bozdag PG, Mutlu HB, Karaduman M, Yildirim M, Khan MA, Alsenan S, Baili J, Nam Y.   +7 more
europepmc   +1 more source