Results 31 to 40 of about 30,779 (263)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Pengaruh Tipe Kepribadian Big Five Personality dan Self-compasion terhadap Loneliness pada Remaja dengan Orang Tua Bercerai [PDF]

, 2021
Irma Rosalida Lubis, Mauna Mauna, Ernita Zakiah, Deni Krisnaputra, Chandra Putri Hafidia Sukmana   +4 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Organizational Citizenship Behavior (OCB) Ditinjau Dari Big Five Personality Pada Karyawan Gen Y di Instansi Z

Jurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Penelitian ini mengungkap relasi Big Five Personality dengan Organizational Citizenship Behavior (OCB) pada karyawan Gen Y di PT Z. Hipotesis mayor menunjukkan hubungan antara Big Five dan OCB, dengan lima hipotesis minor mengaitkan empat dimensi Big ...
Rianda Elvinawanty, Vinanda Vinanda, Stephanie Stephanie, Cherin Prapanca, Arbana Syamantha   +4 more
doaj   +1 more source

Toward a Model of Personality Competencies Underlying Social and Emotional Skills: Insight From the Circumplex of Personality Metatraits

Frontiers in Psychology, 2021
In recent years, there has been a growing interest in social and emotional skills (SES) both in the scientific literature and in social practice. The paper presents an overview of the ways of understanding what SES are and the catalogs thereof. There are
Jan Cieciuch, Jan Cieciuch, Włodzimierz Strus   +2 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Optimization Prediction of Big Five Personality in Twitter Users

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2022
Various kinds of information can be acquired from social media platforms; one of them is on Twitter. User biographical information and tweets are the essential assets for research that can describe the Big Five Personality, including openness ...
Gita Safitri, Erwin Budi Setiawan
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Associations Among the Big Five Personality Traits, Maladaptive Cognitions, and Internet Addiction Across Three Time Measurements in 3 Months During the COVID-19 Pandemic

Frontiers in Psychology, 2021
The present study examined the longitudinal association among the Big Five personality traits, maladaptive cognitions, and Internet addiction during the COVID-19 pandemic.
Yu Tian, Yanli Zhao, Fengling Lv, Ningbo Qin, Peipei Chen   +4 more
doaj   +1 more source