Results 101 to 110 of about 2,463,835 (231)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Great Eurasia: Civilizational Space and Designing the Future

open access: yesЕвразийская интеграция: экономика, право, политика, 2019
The notion of Big Eurasia included in scientific and political lexicon is relatively recent and rapidly filled with new content. Awakening public interest in the Eurasianism coincided with the objective trend of integration States that emerged in Eurasia
Igor F. Kefeli
doaj  

Big Bear Farms

open access: yes, 1962
Black and white photograph of Big Bear Farms in Powell, Ohio. Big Bear Farms provided a good portion of the meats offered by the self service Big Bear chain stores.
Big Bear
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Big Thicket National Preserve Field Research Station Pamphlet

open access: yes
Pamphlet with information on the Field Research Station in Big Thicket National Preserve, including a map and information to reserve the stationThe Big Thicket Collection contains materials relating to the conservation of the Big Thicket area of Texas ...
Big Thicket National Preserve
core  

Zanesville Big Bear store interior

open access: yes, 1948
Canned goods at Zanesville Big Bear location, in June of 1948. Big Bear is responsible for many innovations in the supermarket business. They were the first to introduce motorized counters that were controlled by the cashier. Unique store layouts placing
Big Bear
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Big Thicket National Preserve and Big Thicket Association Anniversary Flyer

open access: yes
Schedule of events for the 25th anniversary of Big Thicket National Preserve and 35th anniversary of the Big Thicket Association, happening concurrentlyThe Big Thicket Collection contains materials relating to the conservation of the Big Thicket area of ...
Big Thicket National Preserve, U.S. National Park Service
core  

Zanesville Big Bear canned goods

open access: yes, 1948
Canned goods at Zanesville Big Bear location, in June of 1948. Big Bear is responsible for many innovations in the supermarket business. They were the first to introduce motorized counters that were controlled by the cashier. Unique store layouts placing
Big Bear
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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