Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez +8 more
wiley +1 more source
Intrinsic Phonons as a Dynamic Control Knob for Catalytic Reactivity in 2D Materials
Intrinsic phonon excitations are demonstrated to serve as a dynamic control knob for catalytic reactivity in 2D materials. Mode‐selective lattice vibrations reconstruct the electronic structure, lower oxygen evolution reaction barriers, establishing a phonon‐engineering paradigm for dynamically regulating electrocatalysis beyond conventional static ...
Kai Ren +5 more
wiley +1 more source
Exploring the Dynamics of Attracting and Retaining Acute Care Psychiatric Registered Nurses: An In-Depth Analysis Using Focus Groups. [PDF]
Ratnapradipa KL +10 more
europepmc +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Toolkit to Promote Collaboration Between Surgeons and Anesthesiologists: Addressing Common Barriers to Perioperative Teamwork. [PDF]
Wei HS +12 more
europepmc +1 more source
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Exploring the Motivations and the Concerns Behind Self-Managed Medication Abortion Done by Purchasing Medication Online: Qualitative Interview Study With US Abortion Seekers Post-Roe. [PDF]
Bosco C, Otenen E, Shih PC.
europepmc +1 more source
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He +9 more
wiley +1 more source
"<i>Dentists are never seen</i>": perspectives on multiple job holding among dentists in Nairobi, Kenya. [PDF]
Ogada C, Rispel LC.
europepmc +1 more source
UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source

