Results 71 to 80 of about 120,911 (240)
Advanced Science, EarlyView.A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu +8 more
wiley +1 more source
Impact of hormone replacement therapy on the histologic subtype of breast cancer [PDF]
, 2018 Objective: Postmenopausal hormone replacement therapy (HRT) is associated with an increase in breast cancer risk, which correlates to the duration of HRT use.
Gueth, Uwe +5 more
core
Advanced Science, EarlyView.A GSH‐responsive MOF nanoplatform acts as a Photothermolysis‐Targeting Conjugate (PTTAC). Through sophisticated step‐wise nuclear delivery, it enables NIR‐II light‐triggered photothermal degradation of BRD4. This precise strategy induces robust immunogenic cell death (ICD) and powerfully synergizes with anti‐PD‐L1 blockade to elicit a potent systemic ...
Luyi Wang +10 more
wiley +1 more source
NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations. [PDF]
, 2013 Inactivating germline mutations in the tumor suppressor gene NF2 cause the hereditary syndrome neurofibromatosis 2, which is characterized by the development of neoplasms of the nervous system, most notably bilateral vestibular schwannoma.
Angelo, Laura S +2 more
core +3 more sources
Consumed by Abdominal Distention
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source
Advanced Science, EarlyView.A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou +10 more
wiley +1 more source
Adrenal insufficiency due to bilateral adrenal metastases - A systematic review and meta-analysis [PDF]
, 2019 Objective: Bilateral adrenal metastases may cause adrenal insufficiency (AI) but it is unclear if screening for AI in patients with bilateral adrenal metastases is justified, despite the potential for adrenal crises. Method: A search using PubMed/Medline,
Falhammar, Henrik +3 more
core +1 more source
Bilateral synchronous male breast cancer
Saudi Medical Journal, 2015 Bilateral synchronous breast cancer is extremely rare. A 75-year-old man presented with a right breast mass, which ulcerated and a lump in the left breast. Right breast examination revealed a breast ulcer 7x10cm with everted edges and complete nipple destruction.
Nwashilli, Nnamdi J. +1 more
openaire +2 more sources
Dual‐Scale Transformer Fusion With Meta Learning for Micro Metastasis Detection in Thyroid Cancer
Advanced Intelligent Systems, EarlyView.A dual‐scale transformer model enhanced by meta‐learning enables accurate detection of tiny metastatic lesions in thyroid cancer. By combining cellular and tissue‐level features, the method outperforms existing models and shows strong adaptability to rare cases with limited data.
Jingtao Wang +5 more
wiley +1 more source