Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Compassionate use of the Seraph® 100 affinity blood filter in pediatric refractory streptococcal septic shock: a case report. [PDF]
Front PediatrMontero-Yeboles R +5 more
europepmc +1 more source
Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review
Clinical Anatomy, EarlyView.ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
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EEG and seizures of pertussis encephalopathy in infants. [PDF]
Front PediatrLuo X, Kuang G, Jiang J, Wei P, Shu X.
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Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Transcatheter edge‐to‐edge repair (TEER) has become an established therapeutic option for patients with severe secondary mitral regurgitation (SMR). While randomized trials and registry data have reported outcomes up to 5 years, longer follow‐up data remain scarce.
Tobias Reithmayer +9 more
wiley +1 more source
Clinical Low Vision Rehabilitation Interventions in Age-Related Macular Degeneration: A Case Report. [PDF]
CureusAl-Tamimi NY, Amer M, Graini FNE.
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Cytometry Part A, EarlyView.ABSTRACT Cell‐in‐cell (CIC) structures are among the most intriguing cellular phenomena occasionally observed in human cancer specimens. Once regarded as incidental findings, accumulating evidence has linked specific CIC subtypes, particularly entosis, to tumor progression and patient prognosis.
Maria V. Leyba‐Mesa +4 more
wiley +1 more source
Editorial: Case reports in thrombosis: 2025. [PDF]
Front Cardiovasc MedSpiezia L.
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Investigation on tunnel stability considering pipe‐roof support with transparent soil technology
Deep Underground Science and Engineering, EarlyView.This study integrates transparent soil technology, 3D reconstruction and numerical simulation to captures the full‐field deformation of shield tunnel instability. Results demonstrate that pipe‐roof support enhances stability via the “soil‐arching barrier effect,” effectively restraining failure wedge development by extending stress transfer paths ...
Zhi Jia +4 more
wiley +1 more source
Color-Contrast Adjustment With a 3D Head-Up System to Aid Capsulorhexis After ICG Staining: Single-Patient Case Report From a Tertiary Center. [PDF]
Case Rep Ophthalmol MedTakada Y +3 more
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