Results 31 to 40 of about 2,042 (145)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

On the dual nature of partial theta functions and Appell-Lerch sums

open access: yes, 2014
In recent work, Hickerson and the author demonstrated that it is useful to think of Appell--Lerch sums as partial theta functions. This notion can be used to relate identities involving partial theta functions with identities involving Appell--Lerch sums.
Andrews   +28 more
core   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong   +9 more
wiley   +1 more source

Bilateral Basic Hypergeometric Series: A Study

open access: yesAnusandhaan - Vigyaan Shodh Patrika, 2018
In the present work, certain transformations and summation formulae for basic bilateral hypergeometric series have been discussed. This study also gives the method of obtaining new transformations and summation formulae for basic bilateral hypergeometric series. Some of the applications have been mentioned.
openaire   +1 more source

Identification and Mechanisms of Osteocyte Subsets Involved in the Pathological Progression of Osteoporosis

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
Osteocyte heterogeneity in bone remains poorly understood. This study identifies six distinct osteocyte subsets in mice, revealing a key subpopulation (BHR‐Ocys) that drives bone loss in osteoporosis. BHR‐Ocys promote osteoclast‐mediated resorption via a novel Sema5a‐Plxna1 signaling axis.
Zengxin Jiang   +8 more
wiley   +1 more source

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng   +14 more
wiley   +1 more source

Slo1 Deficient Myoblast Exosomes‐Derived miR‐222‐3p Inhibits Osteogenic Differentiation via Targeting of STAT3

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Previous research has shown that the conditional knockout of Slo1 in muscle leads to a reduction in muscle strength and inhibits myogenic differentiation. Exosomes are emerging as necessary mediators of the crosstalk between muscle and bones.
Yonghui Wang   +8 more
wiley   +1 more source

On certain relations between products of bilateral hypergeometric series [PDF]

open access: yesProceedings of the Glasgow Mathematical Association, 1957
Darling [3] in 1932 and Bailey [2] in 1933 gave certain theorems on products of hypergeometric series. Again in 1948 Sears [4] used the relation which expresses the series in terms of M other series of the same type to derive transformations between products of both basic and ordinary hypergeometric series. In this paper I give certain general theorems
openaire   +2 more sources

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie   +8 more
wiley   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

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