Results 41 to 50 of about 277,238 (258)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Case series of spontaneous bilateral absorbed cataracts running in a family

Indian Journal of Ophthalmology. Case Reports
There are only a handful of case reports and studies available regarding spontaneously absorbed cataracts and their management, including the surgical techniques and results following the management.
Aparajita Chaudhary, Kriti Bhatt
doaj   +1 more source

Supernumerary maxillary fourth premolar teeth in five related Burmese cats

Journal of Feline Medicine and Surgery Open Reports, 2020
Case series summary This article reports a case series of five Burmese cats with supernumerary teeth. All included cases displayed either unilateral or bilateral supernumerary maxillary fourth premolar teeth.
Roxanne S Emslie, Cedric LC Tutt
doaj   +1 more source

Is Single-Stage Bilateral Knee Arthroscopy a Safe Option?

Revista de la Asociación Argentina de Ortopedia y Traumatología, 2021
Introduction: Single-stage bilateral arthroscopic surgery allows the patient to undergo a single postoperative and rehabilitation period. The aim of this article was to evaluate the functional-clinical outcomes and time to return to work and sports in a ...
Mariano García Bistolfi, Juan Zícaro, Tomás Gorodischer, Carlos Yacuzzi, Matías Costa Paz   +4 more
doaj   +1 more source

A Bilateral Series Involving Basic Hypergeometric Functions [PDF]

, 2005
We prove a summation formula for a bilateral series whose terms are products of two basic hypergeometric functions. In special cases, series of this type arise as matrix elements of quantum group representations.
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A rare case series of bilateral pneumothorax among adult COVID-19 patients reported at a tertiary care hospital in Mizoram, India

Asian Journal of Medical Sciences, 2023
Apart from routine symptoms such as fever, cough, sore throat, myalgia, and dyspnea in severe form of Coronavirus Disease-2019 (COVID-19) infection, very rarely patients can develop worsening of dyspnea due to bilateral pneumothorax.
Lalnuntluanga Sailo , Wendy L Ralte , Zorinsangi Varte , Lalnunmawii Sailo , Micky Zodinpuia , Zorinpuii Khiangte , Ganesh Shanmugasundaram Anusuya   +6 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Bilateral Congenital Upper Eyelid Eversion in Neonates with Lamellar Ichthyosis

TNOA Journal of Ophthalmic Science and Research
Background: Bilateral congenital upper eyelid eversion is a rare but visually alarming condition that presents at birth and is often associated with systemic disorders such as lamellar ichthyosis.
Sangameshwarayya B. Salimath, Saket Rajesh Gandhi, T. M. Poonam   +2 more
doaj   +1 more source

Phacoemulsification of bilateral cataracts in two pet rabbits [PDF]

Open Veterinary Journal, 2018
Two 3 year-old, healthy, client-owned Lop rabbits presented with bilateral cataracts. After performing a physical examination, bloodwork, ocular ultrasonography and electroretinography, both animals were deemed good surgical candidates for ...
Filipe Espinheira Gomes, Ricardo de Matos, Eric Ledbetter   +2 more
doaj   +1 more source