HSD3B1 links ileal steroid metabolism to bile acid regulation in patients with prostate cancer. [PDF]
Fotouhi N +12 more
europepmc +1 more source
A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang +9 more
wiley +1 more source
A Rare Case of Adenosquamous Carcinoma Arising from Intraductal Papillary Neoplasm of the Bile Duct. [PDF]
Kawahito A +4 more
europepmc +1 more source
AI Powered Biobanks From Static Archives to Dynamic Discovery Engines
Large language models (LLMs) provide a potential framework for transforming biobanks from static data repositories into intelligent discovery engines. By enabling unified representation and analysis of multimodal biomedical data, LLM‐based systems facilitate dynamic risk prediction, biomarker identification, and mechanistic interpretation, thereby ...
Wenzhen Yin +5 more
wiley +1 more source
Artificial intelligence-assisted prediction of bile duct bifurcation site in pure laparoscopic donor right hepatectomy: a retrospective feasibility study. [PDF]
Baik J, Oh N, Choi GS, Rhu J, Kim J.
europepmc +1 more source
The psychosocial toll of Dublin III on asylum seekers in the Netherlands
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley +1 more source
Selective intraoperative cholangiography: A retrospective single-centre analysis compared with national data and implications for surgical training. [PDF]
Schwarz J +3 more
europepmc +1 more source
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han +45 more
wiley +1 more source
Biofilm overproduction enhances gastrointestinal stress tolerance and intestinal fitness in <i>Bacillus subtilis</i>. [PDF]
Kunyeit L, Rao R.
europepmc +1 more source
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins +9 more
wiley +1 more source

