Results 331 to 340 of about 234,802 (359)
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A Radioimmunoassay of Bile Acids

Journal of Immunoassay, 1990
A radioimmunoassay for beta-muricholic acid was developed using an antiserum which was prepared by injecting beta-muricholic acid conjugated with bovine serum albumin into rabbits. The antiserum reacted with glyco-beta-muricholic, tauro-beta-muricholic and beta-muricholic acids, but not with other bile acids.
Toshiyuki Chikai   +2 more
openaire   +3 more sources

Bile Acid Sequestrants

The Journal of Clinical Pharmacology, 1990
The bile acid sequestrants, cholestyramine and colestipol, are the drugs of choice for the treatment of patients with hypercholesterolemia caused by increases in LDL‐cholesterol levels without concurrent hypertriglyceridemia (type IIA and type IIB hyperlipoproteinemia). Longitudinal clinical studies with these drugs have shown their ability to slow the
Martin Ast, William H. Frishman
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Bile acid transporters

Current Opinion in Lipidology, 1995
The sodium-dependent bile acid transporters and sodium-independent organic anion transporters are integral membrane glycoproteins that function in the enterohepatic circulation of bile acids. The recent cloning and expression of different classes of bile acid transporters have provided insights into their structure and molecular mechanism.
Peter Oelkers, Paul A. Dawson
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Bile acid malabsorption

Current Treatment Options in Gastroenterology, 2007
Patients with bile acid malabsorption typically present with chronic, watery diarrhea. Bile acids recirculate between the liver and small intestine in the enterohepatic circulation. They are reabsorbed in the distal small intestine, and normally only a small fraction of the bile acid pool is lost to the colon during each cycle.
openaire   +3 more sources

Bile Acid Metabolism

Annual Review of Biochemistry, 1975
INTRODUCTION 233 FORMATION OF BILE ACIDS 234 5fl Bile Acids 234 5~ Bile Acids 236 7c~ Hydroxylation of Cholesterol 237 12o~ Hydroxylation 238 26 Hydroxylation 238 Oxidation of 5fl-Chole~tane-3c~,7~t,12~,26-tetrol 239 METABOLISM OF BILE ACIDS 239 Conju,qation with Glycine and Taurine 240 Esterification with Sulfute and Glucuronic ...
Danielsson H, Sjovall J
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Bile Acid Diarrhea [PDF]

open access: possibleDigestive Diseases, 1998
Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl<sup>–</sup> secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea.
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Bile acid biosynthesis

Biochemistry, 1992
To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology.
David W. Russell, Kenneth D.R. Setchell
openaire   +3 more sources

The Biology of Bile Acids

Archives of Internal Medicine, 1972
In 1967 a conference, largely organized by Leon Schiff, MD, was held in Cincinnati. Many of the investigators active in the field of bile acid metabolism presented their work. The proceedings of that conference, subsequently published in book form, 1 contained most of the information available at that time on the biochemistry and physiology of bile ...
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Bile acids and gestation

Molecular Aspects of Medicine, 2017
There are numerous profound maternal physiological changes that occur from conception onwards and adapt throughout gestation in order to support a healthy pregnancy. By the time of late gestation, when circulating pregnancy hormones are at their highest concentrations, maternal adaptations include relative hyperlipidemia, hypercholanemia and insulin ...
McIlvride, Saraid   +2 more
openaire   +4 more sources

Hepatobiliary transport of bile acid amino acid, bile acid peptide, and bile acid oligonucleotide conjugates in rats

Hepatology, 1999
Uptake of drugs by bile acid carriers could account for the selectivity of drug actions in the gut and liver. We have previously shown that conjugation of xenobiotics with bile acids facilitates their transfer to hepatocytes and ileal enterocytes.
Annette Wickboldt   +4 more
openaire   +2 more sources

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