Results 101 to 110 of about 757,848 (355)
HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury
Advanced Science, EarlyView.Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou +7 more
wiley +1 more source
Microbiome-derived bile acids contribute to elevated antigenic response and bone erosion in rheumatoid arthritis [PDF]
arXiv, 2023 Rheumatoid arthritis (RA) is a chronic, disabling and incurable autoimmune disease. It has been widely recognized that gut microbial dysbiosis is an important contributor to the pathogenesis of RA, although distinct alterations in microbiota have been associated with this disease.
arxiv
Intraductal Papillary Neoplasms of the Bile Duct
International Journal of Hepatology, 2014 Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and is regarded as a biliary counterpart of intraductal papillary mucinous neoplasm of the pancreas.
M. Ohtsuka +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li +11 more
wiley +1 more source
A histometric analysis of chronically rejected human liver allografts: Insights into the mechanisms of bile duct loss: Direct immunologic and ischemic factors [PDF]
, 1989 Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and chronic obliterative arteriopathy. A quantitative histometric analysis was performed to document the extent of bile duct loss, the size of the “vanished ...
Belle, S +3 more
core +1 more source
A Hollow Shell‐Lattice Soft Robot in Flexible Pipelines with Flowing Fluids
Advanced Science, EarlyView.This study proposes a novel shell‐lattice robot with hollow bodies, capable of crawling through pipes with flowing fluids of high velocities and viscosities and mixed with impurities. The robot also features capabilities of crawling with high payloads, in curved pipes, and unthethered crawling. These unique properties make this robot high promising for
Di Guo, Yiqiang Wang, Zhan Kang
wiley +1 more source
Removal of a Large, Intractable Common Bile Duct Stone by Direct Peroral Cholangioscopy
The Korean Journal of Gastroenterology, 2020 ERCP is the standard treatment for common bile duct stones. On the other hand, 10-15% of cases involve intractable common bile duct stones, which cannot be treated by conventional biliary sphincterotomy with a stone retrieval method.
Jun Heo, Min Kyu Jung
doaj +1 more source
Poorly Differentiated Adenocarcinoma with Signet-ring Cell Carcinoma of the Extrahepatic Bile Duct in a 42-year-old Japanese Female: A Case Report [PDF]
, 2010 Poorly differentiated adenocarcinoma without papilla or tubule formation of the extrahepatic bile duct is rare. Here we present a case (a 42-year-old Japanese woman) without either pancreatobiliary maljunction or liver disease.
Hatsuse, Kazuo +6 more
core +1 more source
Recent classifications of the common bile duct injury
Korean Journal of Hepato-Biliary-Pancreatic Surgery, 2014 Laparoscopic cholecystectomy is now a gold standard treatment modality for gallstone diseases. However, the incidence rate of bile duct injury has not been changed for many years.
Kwang-Sik Chun
semanticscholar +1 more source
Advanced Science, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao +27 more
wiley +1 more source