Results 111 to 120 of about 821,293 (407)
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao +13 more
wiley +1 more source
Proteogenomic characterization of cholangiocarcinoma
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
Background Liver metabolites are used to diagnose disease and examine drugs in clinical pharmacokinetics. Therefore, development of an in vitro assay system that reproduces liver metabolite recovery would provide important benefits to pharmaceutical ...
Astia Rizki-Safitri +3 more
doaj +1 more source
Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant +28 more
wiley +1 more source
“Wait-and-See” Strategy for Asymptomatic Patients with Common Bile Duct Stones
Yoon Suk Lee
doaj +1 more source
Endoscopic management of bile duct stones is now the standard of care, but challenges remain with difficult bile duct stones. There are some known factors associated with technically difficult bile duct stones, such as large size and surgically altered ...
Yousuke Nakai +12 more
doaj +1 more source
Liver resections: complications and survival outcome [PDF]
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core +1 more source
This study showed that the pancreaticogastrostomy technique in HPD of biliary tract cancer reduced the incidence of pancreatic fistula from 45% to 12%. In‐hospital mortality was also reduced from 27% to 3%. ABSTRACT Background and Purpose Although hepatopancreaticoduodenectomy (HPD) is effective for margin‐negative curative resection of biliary tract ...
Ryusei Matsuyama +9 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Diagnostics and Treatment of Acute Biliary Pancreatitis [PDF]
The authors have suggested a new diagnostic algorithm to be applied in case of impacted bile duct stone of major duodenal papilla, based on prognosis of acute pancreatitis according to results of analysis of biochemical bile ...
Francev, S. P. +4 more
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