Results 171 to 180 of about 374,517 (260)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Robotic Cholecystectomy and Common Bile Duct Exploration: Multidisciplinary Approach in a Complex Case of Choledocholithiasis. [PDF]

J Clin Med
De Palma C, Delvecchio A, Varvara M, D'Errico F, Decembrino F, Di Giovanni G, Inchingolo R, Memeo R, Tedeschi M.   +8 more
europepmc   +1 more source

Laparoscopic Resection of Caudate Lobe Liver Tumors in Clinical Practice

iNew Medicine, EarlyView.
ABSTRACT The caudate lobe (Couinaud segment I), owing to its deep location in the posterosuperior liver, intimate encirclement by the inferior vena cava (IVC), and close adjacency to the hepatic hilum and major hepatic veins, presents a formidable anatomical challenge for resection.
Dingde Ye, Wenjie Zhang, Qiaoyu Liu, Beicheng Sun, Qingxiang Xu   +4 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Preoperative Diagnosis of the Bile Duct Traumatic Neuroma by Endoscopic Ultrasound-guided Tissue Acquisition: A Case Report. [PDF]

DEN Open
Saito K, Oi S, Yoshida E, Tanaka E, Noujima M, Yamashita N, Shintani S, Nishida A, Iwashita T.   +8 more
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Gel-immersion cholangioscopy-guided laser lithotripsy for difficult common bile duct stones. [PDF]

Endoscopy
Inoue T, Futagami S, Yano M, Doi T, Kitano R, Ito K.   +5 more
europepmc   +1 more source

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

Interdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh, Manjeet Kumar, Kajal Kamra   +2 more
wiley   +1 more source

U.S.A. trends in intrahepatic and bile duct cancers from 1999-2023. [PDF]

Front Gastroenterol (Lausanne)
Berg SW, Billion T, Tauseef A.
europepmc   +1 more source