Results 311 to 320 of about 821,293 (407)

Optimization of Liver Graft Function Using the Poly‐Pharmacological Drug Cocktail CEPT in a Simulated Transplant Model

open access: yesOrgan Medicine, EarlyView.
Stages for drug cocktail Chroman‐1, Emricasan, Polyamine, and Trans‐ISRIB (CEPT) application in the transplantation process: Enhancement of graft function with CEPT treatment evaluated with normothermic machine perfusion. ABSTRACT Background The number of patients in need of a liver transplant far exceeds the supply of available organs.
Anil Kharga   +6 more
wiley   +1 more source

A Case of Obstructive Jaundice due to Bile Duct Tumor Thrombus of Hepatocellular Carcinoma Diagnosed by Peroral Cholangioscopy. [PDF]

open access: yesDEN Open
Kinoshita K   +9 more
europepmc   +1 more source

Genome‐wide analysis of somatic noncoding mutation patterns and mitochondrial heteroplasmic shift in type B1 and B2 thymomas

open access: yesThe Journal of Pathology, EarlyView.
Abstract Type B1 and B2 thymomas are lymphocyte‐rich malignant tumours with few somatic mutations in protein‐coding regions of the nuclear genome; nonetheless, noncoding regions remain uncharacterized. Here, we developed a method to isolate pure thymoma cells from lymphocyte‐rich tissues, and then performed genome‐wide deep sequencing. The total number
Kohei Fujikura   +10 more
wiley   +1 more source

Outcomes after therapeutic SBE-ERCP for choledochojejunal/hepaticojejunal anastomotic stenosis after bile duct injury. [PDF]

open access: yesFront Surg
Shu Y   +12 more
europepmc   +1 more source

Recurrent Self‐Limiting Acute Pancreatitis: Intraductal Papillary Mucinous Neoplasm Requiring Surgery

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Chia‐Hsin Chang   +3 more
wiley   +1 more source

Application of machine learning in constructing a diagnostic model for neonatal biliary atresia

open access: yesPediatric Investigation, EarlyView.
This study included 85 neonates who visited the hospital due to pathological jaundice. Using the basic clinical characteristics and serological examination data of the neonatal period, we developed six machine‐learning (ML) models. Extreme gradient boosting has the maximum potential to diagnose biliary atresia in the neonatal period.
Dingding Wang   +11 more
wiley   +1 more source

Peptidomics in Different Phases of Severe Acute Pancreatitis Model

open access: yesPROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Severe acute pancreatitis (SAP) involves dynamic shifts from inflammation to immunosuppression, where peptidomic profile evolution may reveal prognostic biomarkers. Here, the plasma peptidome of rats with taurocholate‐induced SAP at 1, 3, 6, 12, and 24 h compared with controls was characterized using nLC‐MS/MS.
Roberto Rasslan   +8 more
wiley   +1 more source

Population Pharmacokinetic Analysis of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Patients With Advanced Solid Tumors

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell surface antigen 2 (TROP2)‐directed antibody‐drug conjugate (ADC) developed for the treatment of advanced or metastatic solid tumors. Dato‐DXd demonstrated promising antitumor activity and a manageable safety profile in the first‐in‐human Phase 1 study TROPION‐PanTumor01.
Ying Hong   +11 more
wiley   +1 more source

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