Results 71 to 80 of about 123,324 (263)
Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang+5 more
wiley +1 more source
Structured Lipids: Synthesis, Genetic Engineering, and Applications
ABSTRACT Lipids are essential to the human body, but some can be harmful. As a result, current research focuses on structured lipids (SLs), which are engineered to have specific fatty acid arrangements. These structural modifications can enhance both nutritional and physical properties.
Chandu S. Madankar+5 more
wiley +1 more source
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley +1 more source
ON THE SYMPTOMS OF CHRONIC OBSTRUCTION OF THE COMMON BILE DUCT BY GALLSTONES [PDF]
William Osler
openalex +1 more source
3D printing variation: Teaching and assessing hepatobiliary variants in human anatomy
Abstract Textbook anatomy depiction of the hepatobiliary tree is present in 55%–62% of the population. Misidentification of hepatobiliary variants can lead to bile duct injuries in cholecystectomies. A better understanding of variants has been cited as a key area for improvement in anatomy education.
Christian Myles+2 more
wiley +1 more source
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen+7 more
wiley +1 more source
Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim+7 more
wiley +1 more source
Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source
ACCIDENTAL INJECTION OF BILE DUCTS WITH PETROLATUM AND BISMUTH PASTE [PDF]
Adolph Reich
openalex +1 more source
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu+16 more
wiley +1 more source