Results 81 to 90 of about 123,324 (263)

Population Pharmacokinetic Modeling of Glycochenodeoxycholic Acid 3‐O‐Sulfate (GCDCA‐S) as Endogenous Biomarker of OATP1B3 and OAT3 Transporters

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Endogenous biomarkers for drug transporters are an emerging tool for the assessment of transporter‐mediated drug–drug interactions (DDI). Glycochenodeoxycholic acid 3‐O‐sulfate (GCDCA‐S) has been proposed as a Tier 2 biomarker of hepatic OATP1B3 and renal OAT3 transporters by the International Transporter Consortium.
Yuki Ujihira   +3 more
wiley   +1 more source

Abnormalities of the Bile Ducts*

open access: yesAnnals of Surgery, 1955
Carrington Williams   +1 more
openaire   +4 more sources

Late Pleistocene to Holocene sedimentation in the Great Blue Hole (Lighthouse Reef, Belize): Results from a 30 m long core

open access: yesThe Depositional Record, EarlyView.
A 30 m long sedimentary succession at the bottom of the Belize Blue Hole represents terrestrial cenote (12.5–7.2 ka BP), restricted marine swamp (7.2–5.7 ka BP) and fully marine lagoonal phases (5.7–0 ka BP) on Lighthouse Reef carbonate platform. Post‐glacial and Holocene sea‐level rise largely controlled the sedimentological, faunal and floral changes
Eberhard Gischler   +12 more
wiley   +1 more source

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

open access: yesEye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan   +3 more
wiley   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

open access: yesExploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao   +15 more
wiley   +1 more source

Using Probiotic Consortium to Poultry Feed as a Substitute for Antibiotic Growth Promoters

open access: yesFood Safety and Health, EarlyView.
Probiotic poultry feed to improve broiler performance. ABSTRACT Antibiotic growth promoters (AGPs), once integral to poultry feed formulations for their growth‐enhancing properties, are increasingly associated with the emergence of antibiotic‐resistant strains, posing a significant threat to animal and human health.
Md. Nur Hossain   +5 more
wiley   +1 more source

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