Results 81 to 90 of about 757,848 (355)

The clinicopathological significance and relapse predictive role of tumor microenvironment of intrahepatic cholangiocarcinoma after radical surgery

Cancer, Volume 129, Issue 3, Page 393-404, 1 February 2023., 2023
Abstract Background This study attempts to detect the expression of FoxP3, CD68, CD8α, and PD‐L1 in the tumor microenvironment (TME) of intrahepatic cholangiocarcinoma (ICC), and analyze the relationship between the corresponding cells and clinicopathological characteristics as well as prognosis of ICC.
Yiling Zheng, Ning Huang, Shuwen Kuang, Jing Zhang, Hong Zhao, Jianxiong Wu, Mei Liu, Liming Wang   +7 more
wiley   +1 more source

Choledochal cyst with a twist: Type 1 choledochal cyst and dilated cystic duct with aberrant accessory right hepatic drainage

Journal of Pediatric Surgery Case Reports, 2023
Choledochal cysts are rare cystic dilations of the biliary tree that typically involve the extrahepatic bile duct and more infrequently, the intrahepatic bile ducts. Todani's classification of choledochal cysts is the most referenced system in which five
Pia V. Sodhi, Erin Glennon, Sarah McIntyre, Shailee Lala, Laura Martin, Sandra Tomita   +5 more
doaj  

A Case of Adenomyomatous Hyperplasia of the Extrahepatic Bile Duct

Case Reports in Gastroenterology, 2011
Adenomyomatous hyperplasia is rarely found in the extrahepatic bile duct. A 54-year-old man was referred to our center with a diagnosis of extrahepatic bile duct stenosis which had been detected by endoscopic retrograde choloangiopancreatography ...
Masakatsu Numata, Soichiro Morinaga, Takuo Watanabe, Hiroshi Tamagawa, Naoto Yamamoto, Manabu Shiozawa, Yoichi Kameda, Shinichi Ohkawa, Yasushi Rino, Makoto Akaike, Munetaka Masuda   +10 more
doaj   +1 more source

Biliary Epithelial Apoptosis, Autophagy, and Senescence in Primary Biliary Cirrhosis [PDF]

, 2010
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease characterized serologically by the high prevalence of anti-mitochondrial autoantibodies (AMAs) and histologically by the cholangitis of small bile ducts, eventually followed by ...
Nakanuma, Yasuni, Sasaki, Motoko
core   +4 more sources

Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]

arXiv, 2023
Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv  

Approximate One-Dimensional Models for Monoenergetic Neutral Particle Transport in Ducts with Wall Migration [PDF]

Journal of Computational and Theoretical Transport 46.4 (2017): 242-257, 2016
The problem of monoenergetic neutral particle transport in a duct, where particles travel inside the duct walls, is treated using an approximate one-dimensional model. The one-dimensional model uses three-basis functions, as part of a previously derived weighted-residual procedure, to account for the geometry of particle transport in a duct system ...
arxiv   +1 more source

Geniposidic Acid Targeting FXR “S332 and H447” Mediated Conformational Change to Upregulate CYPs and miR‐19a‐3p to Ameliorate Drug‐Induced Liver Injury

Advanced Science, EarlyView.
Drug abuse exacerbates cholesterol and bile acids burden, causing liver injury. Geniposidic acid targets FXR Ser332 and His447, together with SRC2‐3 recruitment and activated FXR nuclear translocation. Geniposidic acid‐activated FXR can upregulate CYPs to accelerate bile acids clearance and activate miR‐19a‐3p to suppress LXR‐mediated cholesterol ...
Minqi Fan, Yuanhang Xu, Bingxin Wu, Jiachan Long, Caihong Liu, Zuhui Liang, Rong Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Simultaneous Extensive Intraductal Papillary Neoplasm of the Bile Duct and Pancreas: A Very Rare Entity

Case Reports in Surgery, 2016
Intraductal papillary neoplasm of the bile duct (IPNB) is a specific type of bile duct tumor. It has been proposed that it could be the biliary counterpart of the intraductal papillary neoplasm of the pancreas (IPMN-P).
Vor Luvira, Ake Pugkhem, Theerawee Tipwaratorn, Yaovalux Chamgramol, Chawalit Pairojkul, Vajarabhongsa Bhudhisawasdi   +5 more
doaj   +1 more source

A proposed feasible classification of common bile duct duplications based on a newly described variant and review of existing literature

BMC Pediatrics, 2022
Background Duplication of the common bile duct (CBD) is extremely rare among the anatomical variations in the biliary tract system, which presents a septum within the CBD or an accessory CBD.
Huixue Sheng, Guiling Chen, Ming Yang, Hongmei Guan   +3 more
doaj   +1 more source

Bile duct stones, strictures and iatrogenic lesions: studies on early diagnosis and treatment. [PDF]

, 2009
Aims: This study was carried out to investigate the role of common liver function tests, and the degree of common bile duct dilatation in the differential diagnosis of extrahepatic cholestasis, as well as the occurrence, diagnosis and treatment of ...
Karvonen, Jukka
core