Histological insight into the hepatic tissue of the Nile monitor (Varanus niloticus) [PDF]
The liver of reptiles is considered an important study model for the interaction between environment and hepatic tissue. Little is known about the histology of the liver of reptiles. The aim of the current study was to elucidate the histological architecture of the liver of the Nile monitor (Varanus niloticus).
arxiv
Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Adachi Y+48 more
core +1 more source
OGBN O03 Role of Antegrade Stenting in Common Bile Duct Exploration for Biliary Stone Disease; Systematic Review and Metanalysis [PDF]
Amir Abdelhamid+4 more
openalex +1 more source
The postoperative nutritional status of patients with familial adenomatous polyposis who underwent pancreas‐sparing total duodenectomy was better than that of patients who underwent pancreaticoduodenectomy. This study provides the first direct comparison of postoperative nutritional outcomes between patients with pancreas‐sparing total duodenectomy and
Ibuki Fujinuma+11 more
wiley +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie+17 more
wiley +1 more source
PREDICTORS OF FAILURE OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN CLEARING BILE DUCT STONES DURING INDEX PROCEDURE - A PROSPECTIVE STUDY [PDF]
Background: Common bile duct (CBD) stones are known to complicate 10-15% of gallstone diseases. Endoscopic retrograde cholangiopancreatography (ERCP) is the therapeutic modality of choice for bile duct clearance in CBD stones but may fail to achieve ...
Abhishek KAMUNI+5 more
doaj +1 more source
The effectiveness of intraperitoneal chemotherapy using paclitaxel (i.p.‐PTX) in pancreatic ductal adenocarcinoma (PDAC) patients with peritoneal dissemination remains elusive. This study indicated that the i.p.‐PTX therapy may improve survival in selected patients with PDAC, in particular those with occult peritoneal dissemination.
Tomohisa Yamamoto+33 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
CD8+ T cell memory is sustained in mice by hepatic stellate cells
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen+4 more
wiley +1 more source
A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease [PDF]
Scott H. Waddell+17 more
openalex +1 more source