Results 161 to 170 of about 84,202 (354)

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Population Pharmacokinetic Modeling of Glycochenodeoxycholic Acid 3‐O‐Sulfate (GCDCA‐S) as Endogenous Biomarker of OATP1B3 and OAT3 Transporters

Clinical Pharmacology &Therapeutics, EarlyView.
Endogenous biomarkers for drug transporters are an emerging tool for the assessment of transporter‐mediated drug–drug interactions (DDI). Glycochenodeoxycholic acid 3‐O‐sulfate (GCDCA‐S) has been proposed as a Tier 2 biomarker of hepatic OATP1B3 and renal OAT3 transporters by the International Transporter Consortium.
Yuki Ujihira, Viktor Georgiev, Kayode Ogungbenro, Aleksandra Galetin   +3 more
wiley   +1 more source

Improvement of surgical treatment of an acute biliary pancreatitis at elderly and senile patients

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2010
Aim of investigation. To estimate various variants of surgical treatment of acute biliary pancreatitis at patients of over 60 years old, to develop a method of cholecystectomy at the large Hartmann pouch adherent to biliary tracts, to decrease such ...
V. I. Midlenko, A. L. Charyshkin, O. V. Midlenko, I. I. Midlenko, V. Yu. Shchegolev   +4 more
doaj  

Eosinophilic cholecystitis with common bile duct stricture: a rare disease [PDF]

, 2016
Daniel Mehanna, Zainab Naseem, Muslim Mustaev   +2 more
openalex   +1 more source

Bile duct-associated macrophages enter the spotlight in inflammatory cholestatic liver disease

, 2023
Moritz Peiseler, Frank Tacke
openalex   +1 more source

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

Eye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan, Luo Zhang, Yingshi Piao, Yuan Zhang   +3 more
wiley   +1 more source

Su1439 EUS-GUIDED APPROACH AND THERAPY FOR BILE DUCT DISEASES WITH A RENDEZVOUS OR ANTEGRADE METHOD [PDF]

, 2018
Masaki Kuwatani, Kazumichi Kawakubo, Koji Hirata, Ryo Sugiura, Shin Kato, Naoya Sakamoto   +5 more
openalex   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Exploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong, Xin Han, Qiao Yang, Roufen Chen, Liteng Shen, Lei Xu, Lu Wang, Bo Zhu, Dongxin Tang, Shuosheng Zhang, Keda Lu, Mengyun Peng, Gang Cao   +15 more
wiley   +1 more source

Using Probiotic Consortium to Poultry Feed as a Substitute for Antibiotic Growth Promoters

Food Safety and Health, EarlyView.
Probiotic poultry feed to improve broiler performance. ABSTRACT Antibiotic growth promoters (AGPs), once integral to poultry feed formulations for their growth‐enhancing properties, are increasingly associated with the emergence of antibiotic‐resistant strains, posing a significant threat to animal and human health.
Md. Nur Hossain, Saifa Sharmin, Md. Mizanur Rahaman, Md. Masud Rana, Md. Fakruddin, Monzur Morshed Ahmed   +5 more
wiley   +1 more source

Diseases of the Gall-Bladder and Bile-Ducts, Including Gall-Stones.

, 1900

openalex   +2 more sources