Results 231 to 240 of about 242,272 (375)

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

International Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart, Lars Tögel, Maria Giulia Carta, Philip Hetzner, Lina Helbig, Charlotte Zaglas, Maria Ziegler, Robert Stöhr, Annett Hölsken, Juliane Hoyer, Fulvia Ferrazzi, Clemens Neufert, Sebastian Lettmaier, Marianne Pavel, Henriette Golcher, Sarina K. Mueller, Florian Fuchs, Carla E. Schulmeyer, Matthias W. Beckmann, Bernd Wullich, Abbas Agaimy, Andre Reis, Arndt Hartmann, Norbert Meidenbauer, Silvia Spoerl, Florian Haller, Evgeny A. Moskalev   +26 more
wiley   +1 more source

Genetic background and biliary atresia. [PDF]

World J Pediatr Surg
Meng Y, Yang Q, Liu S, Ke X, Zhan J.
europepmc   +1 more source

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang, Steven C. Moore, Sheng Fu, Xiaoyu Wang, Demetrius Albanes, Stephanie J. Weinstein, Kai Yu, Rachael Z. Stolzenberg‐Solomon   +7 more
wiley   +1 more source

Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats

Hepatology, 1997
G. Boigk, L. Stroedter, Hermann Herbst, J. Waldschmidt, E. Riecken, Detlef Schuppan   +5 more
semanticscholar   +1 more source

Organoids in biliary atresia. [PDF]

World J Pediatr Surg
Lui VCH.
europepmc   +1 more source

Results of treatment of patients with gallstone disease and ductal calculi by single-stage laparoscopic cholecystectomy and bile duct exploration [PDF]

, 2014
Eryk Naumowicz, Jacek Białecki, Krzysztof Kołomecki   +2 more
openalex   +1 more source

Ascitic fluid concentrations of fibronectin and cholesterol [PDF]

, 1990
Gerbes, Alexander L., Jüngst, Dieter, Mezger, J., Xie, Yining   +3 more
core  

The impact of a high‐fat diet on liver health in pregnant mice and their offspring: The role of the gut‐liver axis

iMetaOmics, EarlyView.
The study investigated the longitudinal effects of normal and high‐fat diet, showing their differential effects on gut microbiota diversity and gut metabolites, with the latter having a significant impact on increasing liver inflammation and gut microbiota and metabolites disruption.
Qian Gong, Yufei Zhang, Juxiong Liu, Shuai Yuan, Huijie Hu, Yu Cao, Shoupeng Fu, Wenjin Guo   +7 more
wiley   +1 more source

A Novel Bioabsorbable Covered Stent for Advancing Bile Duct Injury Management: A Preclinical Study in a Porcine Model (With Video). [PDF]

DEN Open
Miyazawa M, Aikawa M, Takashima J, Kobayashi H, Minagawa T, Itano O, Ohnishi S.   +6 more
europepmc   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source