Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D+10 more
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Malignant diseases maifesting jaundice as a main symptom -Diagnosis and treatment to improve the poor survival in carcinoma of the bile duct and pancreatic head - [PDF]
Primary malignant diseases manifesting jaundice as a main symptom are the carcinomas of the bile duct and the pancreatic head, both of which have very poor survival rates after surgical resection or other treatments.
Mimura, Hisashi
core +1 more source
Tissue-Engineered Bile Ducts for Disease Modeling and Therapy [PDF]
Recent biotechnical advances in the in vitro culture of cholangiocytes and generation of bioengineered biliary tissue have a high potential for creating biliary tissue to be used for disease modeling, drug screening, and transplantation. For the past few decades, scientists have searched for a source of cholangiocytes, focused on primary cholangiocytes
Wang, Zhenguo+4 more
openaire +4 more sources
A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations [PDF]
The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a form of symptomatic cholelithiasis occurring in young adults, characterized by recurrence of symptoms after cholecystectomy and presence of hepatolithiasis.
Anapaz, V+7 more
core +1 more source
Benign disease of the common bile duct
Abstract The incidence of common bile duct (CBD) pathology in a group of patients with benign biliary disease (n = 505) was found to be 23.2 per cent. The spectrum included 111 patients (90.2 per cent) with CBD stones, 37 of whom (33.3 per cent) had no symptoms or findings pre-operatively indicating CBD involvement.
R. Saxena+6 more
openaire +3 more sources
Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H.+10 more
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Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini+25 more
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Bile acids content in brain of common duct ligated rats
Introduction. Cholestasis leads to liver cell death, fibrosis, cirrhosis, and eventually liver failure. Bile duct ligated rats constitute an interesting model to study the mechanism of cholestasis, and its action on several organs and tissues, including ...
Valeria Tripodi, M.D.+3 more
doaj +1 more source
Cell proliferation and oncogene expression after bile duct ligation in the rat: Evidence of a specific growth effect on bile duct cells [PDF]
The proliferative response of the rat liver was measured after temporary or permanent total biliary obstruction (BDO) and in different regions after selective ligation of the lobar ducts draining the right 60% of the hepatic mass.
Azzarone, A+8 more
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Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco+4 more
core +1 more source