Results 81 to 90 of about 242,272 (375)

Cholestasis‐induced adaptive remodeling of interlobular bile ducts

Hepatology, 2016
Cholestasis is a common complication in liver diseases that triggers a proliferative response of the biliary tree. Bile duct ligation (BDL) is a frequently used model of cholestasis in rodents.
N. Vartak, A. Damle-Vartak, B. Richter, O. Dirsch, U. Dahmen, S. Hammad, J. Hengstler   +6 more
semanticscholar   +1 more source

CHOLANGIOSCOPY IN BILE DUCT DISEASE: a case series [PDF]

Arquivos de Gastroenterologia, 2014
Context Direct endoscopic visualization of biliopancreatic duct is certainly one of the greatest advances of therapeutic endoscopy. The use of a single-operator cholangioscopy platform (SpyGlass) is a promising technique in the evaluation of diseases such as indeterminate biliary stricture and giant choledocholitiasis. This is the first Brazilian case
MOURA, Eduardo Guimarães Hourneaux de, FRANZINI, Tomazo, MOURA, Renata Nobre, CARNEIRO, Fred Olavo Aragão Andrade, ARTIFON, Everson Luiz de Almeida, SAKAI, Paulo   +5 more
openaire   +6 more sources

Role of Tunneling Nanotubes in Arachidonic Acid Transfer and Macrophage Function Reprogramming in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen, Shangyumeng Zhao, Xiaoli Xie, Jiaqi Wang, Miao Su, Lixian Zhang, Ruolin Cui, Dongqiang Zhao   +7 more
wiley   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Biochemical research of hepatoprotective activity of Lavaflam tablets in rats with subchronic hepatitis

Current Issues in Pharmacy and Medical Sciences, 2020
Liver damage is a common problem all over the world. To optimize the drug provision in the limited financing of the Health Care System, it is necessary to develop new drugs with hepatoprotective properties that are highly effective and of low cost.
Aslanian Milena A., Bobrytska Larisa A., Bereznyakova Natalya L., Shpychak Oleg S., Hrytsenko Vita I., Germanyuk Tamara A., Ivko Tatiana I.   +6 more
doaj   +1 more source

In Situ Assembly of Fluorogenic RNA for Screening Natural Anti‐Liver Fibrosis Products via Dynamic Visualization of COL1A1 mRNA

Advanced Science, EarlyView.
This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai, Li‐Zeng Zhu, Changfa Shao, Zheng Yin, Qun Liu, Yu Gu, Bin Liu   +6 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Six Rare Biliary Tract Anatomic Variations: Implications for Liver Surgery

Eurasian Journal of Medicine, 2011
Objective: The variations in the anatomy of the biliary tract need to be recognized in modern liver surgery. The purpose of this clinical and anatomical study is to describe several novel biliary tract variations and to outline their practical importance
Daniel V. Kostov, Georgi L. Kobakov
doaj  

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D, Arcidiacono, Pg, Capurso, G., Cardinale, V, Carpino, G, Doglioni, C, Gaudio, E, Pedica, F, Petrone, Mc, Severi, C, Zaccari, P   +10 more
core   +1 more source

Iatrogenic bile duct injury: a population-based study of 152 776 cholecystectomies in the Swedish Inpatient Registry.

Archives of Surgery, 2006
HYPOTHESIS Older age, male sex, and low yearly hospital volume of cholecystectomy may increase the risk of bile duct injury (BDI), whereas the use of intraoperative cholangiography may decrease the risk.
A. Waage, M. Nilsson
semanticscholar   +1 more source