DEN Open, Volume 7, Issue 1, April 2027.ABSTRACT During peroral cholangioscopy‐guided electrohydraulic lithotripsy (EHL), stone fragmentation obscures the visual field (the “snowstorm effect”), and visualization quality has been assessed only subjectively. This proof‐of‐concept study explored the feasibility of a deep‐learning method for objectively quantifying visualization quality during ...
Hideki Kamada +9 more
wiley +1 more source
Clinical safety study of laparoscopic common bile duct exploration and primary suture in elderly patients: a new strategy for the treatment of stones. [PDF]
BMC SurgYe HW +5 more
europepmc +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2692-2707, December 2026.ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins +9 more
wiley +1 more source
Laparoscopic Common Bile Duct Exploration for Choledocholithiasis in a Patient with Situs Inversus Totalis and Prior Total Gastrectomy with Roux-en-Y Reconstruction: A Case Report. [PDF]
Surg Case RepNagata T +5 more
europepmc +1 more source
Clinical and Translational Discovery, Volume 6, Issue 6, December 2026.1. Prevention strategies should be stratified by preoperative cholangitis status. 2. For pre‐existing cholangitis, therapeutic antibiotics plus urgent drainage are essential; ENBD and stents show similar efficacy. 3. Early biliary drainage is the cornerstone of treatment; endoscopic drainage is preferred, with PTCD/EUS‐BD as second‐line. 4.
Hao‐Xin Chen, Jun Yao
wiley +1 more source
Free‐Breathing Hepatic Oxygen Extraction Fraction (OEF) Mapping Using Radial GESSE
Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2840-2847, December 2026.ABSTRACT Purpose Noninvasive assessment of hepatic oxygenation is relevant for evaluating liver both in acute and long‐term liver pathologies. However, existing methods are limited to single‐slice acquisitions and require breath‐holding. This study aims to develop and evaluate a motion‐robust technique for whole‐liver oxygen extraction fraction (OEF ...
Ke Zhang +9 more
wiley +1 more source
Risk factors for bile leakage after laparoscopic common bile duct exploration in older patients with choledocholithiasis. [PDF]
World J Gastrointest SurgXiong RF +4 more
europepmc +1 more source
Total Neoadjuvant Treatment for Esophageal Adenocarcinoma With Oligometastases: TNT‐OES‐1 Trial
International Journal of Cancer, Volume 159, Issue 10, Page 2552-2561, 15 November 2026.Total neoadjuvant therapy could combine the potentially strong systemic effect of FLOT chemotherapy with the good locoregional control of CROSS chemoradiotherapy. While total neoadjuvant therapy is increasingly used in rectal cancer, its potential in gastroesophageal cancer remains largely unexplored.
Charlène J. van der Zijden +12 more
wiley +1 more source
Laparoscopic common bile duct exploration for retained biliary stent removal after one anastomosis gastric bypass: A case report. [PDF]
Int J Surg Case RepLevy J, Keidar A, Eldar SM, Abu Abeid A.
europepmc +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3902-3913, November 2026.Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub +3 more
wiley +1 more source