Results 291 to 300 of about 122,669 (361)

Limy Bile in the Common Bile Duct

open access: yesInternational Journal of Clinical Practice, 1961
openaire   +2 more sources

Validation of Intravoxel Incoherent Motion MRI Using Perfused Explanted Human Livers

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Evaluate the feasibility of using perfused explanted human livers for validating intravoxel incoherent motion (IVIM). Methods Eight (n = 8) explanted livers from deceased donors were obtained. The portal vein and hepatic artery of each explanted liver were connected to a perfusion system.
Gregory Simchick   +6 more
wiley   +1 more source

Highly Reproducible, Vendor‐Agnostic, Motion‐Insensitive Liver PDFF Mapping at 0.55T, 1.5T, and 3T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and validate a vendor‐agnostic, motion‐insensitive proton‐density fat‐fraction (PDFF) quantification method. Methods Flip‐angle‐modulated (FAM) 2D chemical‐shift‐encoded (CSE) MRI for PDFF quantification was implemented in both the vendor‐agnostic platform Pulseq (“Pulseq‐FAM”) and one vendor‐specific platform (“GE‐specific ...
Jiayi Tang   +27 more
wiley   +1 more source

Bile Acid Binding Resins Improve Glucagon Receptor Agonist‐Mediated Weight Loss in Diet‐Induced Obese Mice

open access: yesObesity, EarlyView.
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Teayoun Kim   +9 more
wiley   +1 more source

Optimization of Liver Graft Function Using the Poly‐Pharmacological Drug Cocktail CEPT in a Simulated Transplant Model

open access: yesOrgan Medicine, EarlyView.
Stages for drug cocktail Chroman‐1, Emricasan, Polyamine, and Trans‐ISRIB (CEPT) application in the transplantation process: Enhancement of graft function with CEPT treatment evaluated with normothermic machine perfusion. ABSTRACT Background The number of patients in need of a liver transplant far exceeds the supply of available organs.
Anil Kharga   +6 more
wiley   +1 more source

Genome‐wide analysis of somatic noncoding mutation patterns and mitochondrial heteroplasmic shift in type B1 and B2 thymomas

open access: yesThe Journal of Pathology, EarlyView.
Abstract Type B1 and B2 thymomas are lymphocyte‐rich malignant tumours with few somatic mutations in protein‐coding regions of the nuclear genome; nonetheless, noncoding regions remain uncharacterized. Here, we developed a method to isolate pure thymoma cells from lymphocyte‐rich tissues, and then performed genome‐wide deep sequencing. The total number
Kohei Fujikura   +10 more
wiley   +1 more source

Application of machine learning in constructing a diagnostic model for neonatal biliary atresia

open access: yesPediatric Investigation, EarlyView.
This study included 85 neonates who visited the hospital due to pathological jaundice. Using the basic clinical characteristics and serological examination data of the neonatal period, we developed six machine‐learning (ML) models. Extreme gradient boosting has the maximum potential to diagnose biliary atresia in the neonatal period.
Dingding Wang   +11 more
wiley   +1 more source

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