Results 311 to 320 of about 700,010 (401)

A prediction model for genetic cholestatic disease in infancy using the machine learning approach

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Diagnostic algorithm for cholestatic infants. Abstract Objectives Cholestasis in infancy poses a complex clinical conundrum for pediatric hepatologists, warranting timely diagnosis, especially for genetic diseases. This study aims to create machine learning (ML)‐based prediction models, referred to as Jaundice Diagnosis Easy for Baby (JADE‐B), to ...
Chi‐San Tai   +9 more
wiley   +1 more source

Prognosis of pediatric‐onset inflammatory bowel disease associated with primary sclerosing cholangitis: A population‐based study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To assess whether the prognosis of pediatric‐onset inflammatory bowel disease (IBD) is influenced by its association with primary sclerosing cholangitis (PSC) considering medical treatment, bowel resection, risk of cancer, and mortality. Methods A retrospective population‐based study was conducted using data from the EPIMAD Registry,
Marie‐Laura Godet   +10 more
wiley   +1 more source

Impact of Wound Protectors on Complications Following Pancreaticoduodenectomy: A National Surgical Quality Improvement Program Analysis of 20 960 Patients

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background Wound protectors (WPs) have been shown to decrease postoperative wound complications, yet limited data exist supporting WP for pancreaticoduodenectomies, with limited uptake in practice. We evaluated the effect of WP in pancreaticoduodenectomies on surgical site infections (SSIs) and serious complications.
Tyrell Wees   +6 more
wiley   +1 more source

The Role of KRAS Status Among Patients Undergoing Staged Versus Simultaneous Resection for Synchronous Colorectal Liver Metastases

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background This study aimed to evaluate the impact of surgical timing—simultaneous versus staged resection—on outcomes of patients with colorectal liver metastases (CRLM) in relation to KRAS mutation status, which is a key factor affecting prognosis.
Andrea Baldo   +17 more
wiley   +1 more source

Implications of an Isolated Positive Vascular Groove After Whipple for Pancreatic Adenocarcinoma: A Single Institution, Retrospective Analysis

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objective The vascular groove (VG) is no longer considered a resection margin but rather a surface of involvement. The clinical significance of an isolated VG+ remains debated. Therefore, this study evaluates the impact of isolated VG+, with or without vein resection, on overall survival (OS) and disease‐free survival (DFS ...
Callie A. Hlavin   +9 more
wiley   +1 more source

P53 Function Status Correlates With Overall Survival in Patients With Resected Pancreatic Cancer

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background The P53 gene is the most common tumor‐suppressor gene mutated in pancreatic ductal adenocarcinoma (PDAC). The gene's normal function is critical for regulation of replication, DNA repair, and apoptosis. The purpose of our study is to determine the impact of the various P53 mutation subtypes on survival in resected PDAC. Methods This
Hui Chen   +8 more
wiley   +1 more source

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