Results 321 to 330 of about 719,832 (406)

Therapeutic potential of tetrahydroxylated bile acids in reducing liver injury: Insights from the Zfyve19−/− mouse model

open access: yesPediatric Investigation, EarlyView.
THBA (3α,6α,7α,12α‐Tetrahydroxy‐10β,13β‐pentanoic acid) administration can alleviate cholestatic liver injury, hepatocellular necrosis, inflammatory response, bile duct hyperplasia, and portal fibrosis in the Zfyve19−/− mouse model. This evaluation encompasses various parameters, including serum biochemistry, liver histology, immunostaining, and ...
Li Wang   +8 more
wiley   +1 more source

Machine Learning‐Based Risk‐Adjusted CUSUM Control Chart for Monitoring Readmission Rate Following PTBD Catheter Placement

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT Percutaneous transhepatic biliary drainage (PTBD) catheter placement is known to have a high readmission rate. This work focuses on monitoring the change in readmission rate after a new clinical paradigm for post‐procedural care is implemented for the PTBD procedures.
Muhammed Aljifri   +2 more
wiley   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes   +2 more
wiley   +1 more source

Quality of Life Among Thai Patients With Advanced Cancer: Findings From the APPROACH Study

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Cancer is the leading cause of death in Thailand, but quality of life with cancer is not well understood. Thai patients had relatively high quality of life, but the pervasiveness of self‐blame and its association with reduced quality of life, and the large proportion with depressive symptoms, stresses the need for mental health care.
Waranee Bunchuailua   +4 more
wiley   +1 more source

Epidemiology of hypospadias in China: A nationwide surveillance‐based study, 2010–2020

open access: yesAndrology, EarlyView.
Abstract Background The prevalence of hypospadias varied internationally. However, epidemiological data on hypospadias in contemporary China remain limited. Objectives We aim to examine the epidemiological characteristics of hypospadias in Chinese population.
Chen Zhiyu   +7 more
wiley   +1 more source

Comparative Outcomes of Reinforced Tension‐Line Sutures Versus Standard Closure Techniques in Patients Undergoing Laparotomy: A Systematic Review and Meta‐Analysis

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background The reinforced tension‐line suture (RTLS) technique distributes mechanical stress more evenly than traditional closure when closing a laparotomy wound, potentially reducing incisional hernia (IH) risk. We aimed to compare outcomes of RTLS versus standard closure techniques in patients undergoing laparotomy. Methods Systematic search
Rama H. G. Mikhail   +6 more
wiley   +1 more source

Integrating Dialysis in Ex Situ Machine Perfusion: A Systematic Review and Meta‐Analysis of Outcomes

open access: yesArtificial Organs, EarlyView.
Dialysis‐enhanced EVMP effectively maintains biochemical homeostasis, potentially mitigating metabolic stress and extending perfusion duration. Functional outcomes varied depending on the organ type, with the most pronounced benefits observed in cardiac perfusion.
Yomna E. Dean   +12 more
wiley   +1 more source

Biliary Glutathione as a Potential Marker for Viability Assessment of Cholangiocytes During Normothermic Machine Perfusion of Livers

open access: yesArtificial Organs, EarlyView.
This study identifies biliary glutathione concentration during normothermic machine perfusion as a potential biomarker for biliary viability. Increasing GSH levels correlate with fewer biliary complications post‐transplant, supporting its role in assessing graft quality and improving decision‐making in liver transplantation.
Christina Bogensperger   +10 more
wiley   +1 more source

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