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Bioengineered bile ducts recapitulate key cholangiocyte functions
Biofabrication, 2018Investigation of diseases of the bile duct system and identification of potential therapeutic targets are hampered by the lack of tractable in vitro systems to model cholangiocyte biology.
Chen Chen +10 more
semanticscholar +1 more source
2021
Cholangiopathies affect the biliary tree via various pathophysiological mechanisms. Research on biliary physiology and pathology, however, is hampered by a lack of physiologically relevant in vitro models. Conventional models, such as two-dimensional (2D) monolayers and organoids, fail to replicate the structural organization of the bile duct, and both
Rebecca G. Wells +2 more
openaire +2 more sources
Cholangiopathies affect the biliary tree via various pathophysiological mechanisms. Research on biliary physiology and pathology, however, is hampered by a lack of physiologically relevant in vitro models. Conventional models, such as two-dimensional (2D) monolayers and organoids, fail to replicate the structural organization of the bile duct, and both
Rebecca G. Wells +2 more
openaire +2 more sources
Archives of Surgery, 1985
The diagnosis of biliary duct varices and portal vein occlusion should be considered when nodular or notched defects in the wall of the biliary duct system are shown by cholangiography or when pedunculated vascular structures in the bile ducts are seen at surgery.
Benjamin T. Jackson +5 more
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The diagnosis of biliary duct varices and portal vein occlusion should be considered when nodular or notched defects in the wall of the biliary duct system are shown by cholangiography or when pedunculated vascular structures in the bile ducts are seen at surgery.
Benjamin T. Jackson +5 more
openaire +3 more sources
Radiología (English Edition), 2015
Bile duct tumors are benign or malignant lesions which may be associated to risk factors or potentially malignant lesions. They constitute an heterogenous entities group with a different biological behavior and prognosis according to location and growth pattern.
G. Martín-Benítez +4 more
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Bile duct tumors are benign or malignant lesions which may be associated to risk factors or potentially malignant lesions. They constitute an heterogenous entities group with a different biological behavior and prognosis according to location and growth pattern.
G. Martín-Benítez +4 more
openaire +3 more sources
1988
Gallbladder stones form the majority of biliary disease, and are conveniently detected by ultrasonography (US).
Ian A.D. Bouchier, Malcolm C. Bateson
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Gallbladder stones form the majority of biliary disease, and are conveniently detected by ultrasonography (US).
Ian A.D. Bouchier, Malcolm C. Bateson
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Paraganglioma of the Bile Duct*
Southern Medical Journal, 2001We report the case of a 28-year-old woman with a 3-month history of right upper quadrant abdominal pain. Medical history and physical examination were unremarkable. Abdominal ultrasonography showed a dilated gallbladder, suggestive of gallstones, without bile duct dilatation. Serum chemistry values were normal. Laparoscopic cholecystectomy was planned,
M, Caceres +3 more
openaire +2 more sources
Rhabdomyosarcoma of the bile ducts
Journal of Pediatric Surgery, 1977Rhabdomyosarcoma is a rare malignant neoplasm of the biliary tract. Including all the historical recent probable, and established cases that are carefully classified by Hayes and Synder, only 24 cases have been reported to date. Because of the extreme rarity of this tumor in this location, correct diagnosis was not made until second laparotomy or ...
Carol Leitner +2 more
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Rhabdomyosarcoma of the Bile Ducts
European Journal of Pediatric Surgery, 1981A 4 and one half-year-old girl with rhabdomyosarcoma of the bile ducts who was managed by excision of the entire tumour mass followed by chemotherapy has survived four years without evidence of recurrence.
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Clinics in Liver Disease, 2003
Drug-induced bile duct injury related prolonged or chronic cholestasis is recognized as a common side effect of treatment with several drugs. The severity and duration of the clinical symptoms suggest that this increase in number of reports is not only related to clinician and pathologists being increasingly aware of the condition, but also may ...
Jacques Rahier +2 more
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Drug-induced bile duct injury related prolonged or chronic cholestasis is recognized as a common side effect of treatment with several drugs. The severity and duration of the clinical symptoms suggest that this increase in number of reports is not only related to clinician and pathologists being increasingly aware of the condition, but also may ...
Jacques Rahier +2 more
openaire +3 more sources
Archives of Surgery, 1963
Carcinoma of the major extrahepatic and intrahepatic bile ducts, although infrequently encountered, merits consideration in every patient having obstructive jaundice. The correct preoperative diagnosis is seldom made. The operative diagnosis is difficult because of the limited anatomical boundaries and the difficulty of thorough exploration of the ...
E. Lee Strohl +3 more
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Carcinoma of the major extrahepatic and intrahepatic bile ducts, although infrequently encountered, merits consideration in every patient having obstructive jaundice. The correct preoperative diagnosis is seldom made. The operative diagnosis is difficult because of the limited anatomical boundaries and the difficulty of thorough exploration of the ...
E. Lee Strohl +3 more
openaire +3 more sources