Results 101 to 110 of about 19,725 (236)

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Nutritional status of patients with biliary atresia and autoimmune hepatitis related to serum levels of vitamins A, D and E Estado nutricional de pacientes com atresia biliar e hepatite autoimune e relação com os níveis séricos de vitaminas A, D e E

open access: yesArquivos de Gastroenterologia, 2009
CONTEXT: Chronic liver disease may induce to malabsorption of lipids and fat-soluble vitamins, leading to injury of nutritional status. OBJECTIVES: To evaluate the nutritional status of pediatric-age patients with autoimmune hepatitis and biliary atresia
Margareth L. G. Saron   +2 more
doaj   +1 more source

Epidemiology of hypospadias in China: A nationwide surveillance‐based study, 2010–2020

open access: yesAndrology, Volume 14, Issue 3, Page 880-889, March 2026.
Abstract Background The prevalence of hypospadias varied internationally. However, epidemiological data on hypospadias in contemporary China remain limited. Objectives We aim to examine the epidemiological characteristics of hypospadias in Chinese population.
Chen Zhiyu   +7 more
wiley   +1 more source

Associations of Intraoperative Hypotension and Vasopressor Administration With Postoperative Acute Kidney Injury in Children Undergoing Liver Transplantation: A Retrospective Cohort Study

open access: yesPediatric Anesthesia, Volume 36, Issue 3, Page 240-248, March 2026.
ABSTRACT Background Both intraoperative hypotension (IOH) and vasopressor administration are independently associated with postoperative acute kidney injury (AKI) in adults undergoing major noncardiac surgery. Whether these associations extend to children undergoing major noncardiac surgery, such as liver transplantation, remains unknown.
Theodora Wingert   +7 more
wiley   +1 more source

Alterations of gut microbiota in infants with biliary atresia identified by 16S rRNA-sequencing

open access: yesBMC Pediatrics
Background Biliary atresia (BA) is a severe neonatal disease with progressive intra- and extra-hepatic bile ducts inflammation and hepatic fibrosis.
Fei Liu   +6 more
doaj   +1 more source

Changing perspectives on liver transplantation in 1988. [PDF]

open access: yes, 1988
After liver transplantation for cancer, there is a high incidence of disease recurrence within 18 to 36 months for most tumors, although there are a small number of long-term survivors.
Gordon, RD, Starzl, TE
core  

Adenovirus Disease Following Pediatric Liver Transplantation: 10‐Year Experience From a Large Pediatric Transplant Program

open access: yesPediatric Transplantation, Volume 30, Issue 3, March 2026.
The incidence of adenovirus disease is high (26%) after pediatric liver transplantation, with the majority of the infections occurring in the first 3 months post‐transplant highlighting the need for a high index of suspicion, early identification, and close follow‐up of adenovirus infection.
Anna M. Banc‐Husu   +8 more
wiley   +1 more source

Incidence and outcome of biliary atresia in Shanghai, China from 2015 to 2016: a cohort study

open access: yesBMJ Paediatrics Open
Demographic characteristics and clinical data of all newly diagnosed biliary atresia patients in Shanghai were collected from 1 January 2015 to 31 October 2016.
Gong Chen   +5 more
doaj   +1 more source

Biliary atresia in Slovenia Congenital extrahepatic biliary atresia in children in Slovenia – epidemiological retrospective data

open access: yesZdravniški Vestnik, 2013
Backg round: The objective of this study was to investigate the history, clinical, laboratory, imaging data and outcome of children with biliary atresia in Slovenia.
Petja Fister   +4 more
doaj  

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