Results 131 to 140 of about 226,924 (326)

Alpha-1 antitrypsin deficiency [PDF]

, 2001
α-1 antitrypsin is synthesised in the liver and protects lung alveolar tissues from destruction by neutrophil elastase. α-1 antitrypsin deficiency is a common autosomal recessive condition (1:1600 to 1:1800) in which liver disease results from retention ...
Primhak, R.A., Tanner, M.S.
core   +2 more sources

Ovarian Aging: Mechanisms, Age‐Related Disorders, and Therapeutic Interventions

MedComm, Volume 6, Issue 12, December 2025.
A comprehensive overview of the molecular mechanisms underlying ovarian aging, its association with age‐related diseases, and potential therapeutic interventions. Ovarian aging involves DNA damage, mitochondrial dysfunction, oxidative stress, telomere attrition, and follicular depletion, driving age‐related infertility, menopause, and multiple systemic
Xingyu Liu, Yuanqu Zhao, Yanzhi Feng, Shixuan Wang, Jinjin Zhang   +4 more
wiley   +1 more source

Nutritional status of patients with biliary atresia and autoimmune hepatitis related to serum levels of vitamins A, D and E Estado nutricional de pacientes com atresia biliar e hepatite autoimune e relação com os níveis séricos de vitaminas A, D e E

Arquivos de Gastroenterologia, 2009
CONTEXT: Chronic liver disease may induce to malabsorption of lipids and fat-soluble vitamins, leading to injury of nutritional status. OBJECTIVES: To evaluate the nutritional status of pediatric-age patients with autoimmune hepatitis and biliary atresia
Margareth L. G. Saron, Helena T. Godoy, Gabriel Hessel   +2 more
doaj   +1 more source

The Current Status of Liver Transplantation. [PDF]

, 1971
More than thirty patients have now undergone liver transplantation in Denver, some more than once, and survivals of up to two and a half years have been achieved. Through this and other experience it has been learned that graft viability is more critical
Starzl, Thomas E
core   +1 more source

Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis [PDF]

, 2005
Chao‐Cheng Huang, Jiin‐Haur Chuang, Ming-Huei Chou, Chia‐Lin Wu, Ching-Mei Chen, Chih‐Chi Wang, Yaw‐Sen Chen, Chao‐Long Chen, Ming‐Hong Tai   +8 more
openalex   +1 more source

Core Indicator Set for Measuring Quality of Care in Necrotising Enterocolitis: A European Delphi Study

Acta Paediatrica, Volume 114, Issue 12, Page 3284-3297, December 2025.
ABSTRACT Aim Inconsistent guidelines and practice variations in necrotising enterocolitis (NEC) hamper care improvements. A universally accepted quality indicator set is needed to standardise and improve care throughout Europe. We aimed to establish a core set relevant to NEC patients and experts.
Otis C. van Varsseveld, Irene de Haro Jorge, Daniel Rossi, Marlinde van der Kamp, Mohamed Riadh Boukhris, Miriam Duci, Johannes W. Duess, Simon Eaton, Elisabeth M. W. Kooi, Martin Lacher, Lucas E. Matthyssens, Carmen Mesas Burgos, Marc Miserez, Lorenzo Norsa, Elena Palleri, Rony Sfeir, Marie Spruce, Marijn J. Vermeulen, Jan. B. F. Hulscher, Jordi Prat Ortells   +19 more
wiley   +1 more source

Association Between Nucleated Red Blood Cell Counts and the Mortality in Patients With Liver Diseases: An Analysis of the MIMIC‐IV Database

Journal of Cellular and Molecular Medicine, Volume 29, Issue 23, December 2025.
ABSTRACT Liver disease is a leading cause of death worldwide. Nucleated red blood cells (NRBCs) are associated with high mortality and poor outcomes in patients with severe illnesses. However, the relationship between NRBCs and severe liver disease remains unclear. Potential confounding effects were managed using propensity score matching.
Yuanyuan Zhu, Danyang Yan, Fang Peng, Run Yao, Ning Li   +4 more
wiley   +1 more source

Alterations of gut microbiota in infants with biliary atresia identified by 16S rRNA-sequencing

BMC Pediatrics
Background Biliary atresia (BA) is a severe neonatal disease with progressive intra- and extra-hepatic bile ducts inflammation and hepatic fibrosis.
Fei Liu, Ru Wei, Xiaogang Xu, Menglong Lan, Boyuan Tao, Zijian Liang, Jixiao Zeng   +6 more
doaj   +1 more source

Elevated Serum Bile Acids Predict Poor Liver Outcomes in Children With Alagille Syndrome: Results From the GALA Study Group

Liver International, Volume 45, Issue 12, December 2025.
ABSTRACT Background and Aim Alagille syndrome (ALGS) is a rare disorder characterised by cholestasis and extrahepatic manifestations. Given the current era of ileal bile acid transporter (IBAT) inhibitor therapies that reduce serum bile acid (SBA) levels, we evaluated whether SBA predicts liver disease outcomes in ALGS.
Carla Fiorella Murillo Perez, Shannon M. Vandriel, Emmanuel M. Gonzales, Jian‐She Wang, Li‐Ting Li, Huiyu She, Irena Jankowska, Piotr Czubkowski, Dorota Gliwicz‐Miedzińska, Emmanuel Jacquemin, Jérôme Bouligand, Lorenzo D'Antiga, Emanuele Nicastro, Björn Fischler, Henrik Arnell, Susan M. Siew, Michael Stormon, Kathleen M. Loomes, David A. Piccoli, Elizabeth B. Rand, James E. Squires, Saul J. Karpen, Rene Romero, Mureo Kasahara, Zerrin Önal, Étienne Sokal, Tanguy Demaret, Sabina Wiecek, Florence Lacaille, Dominique Debray, Winita Hardikar, Sahana Shankar, Pamela L. Valentino, Shikha S. Sundaram, Noelle H. Ebel, Jeffrey A. Feinstein, Orith Waisbourd‐Zinman, Henry C. Lin, Nathalie Rock, Henkjan J. Verkade, M. Kyle Jensen, Catalina Jaramillo, Kyung Mo Kim, Seak Hee Oh, Jernej Brecemiclj, Seema Alam, Giuseppe Indolfi, Niviann Blondet, Rima Fawaz, Silvia Nastasio, Pier Luigi Calvo, Gabriella Nebbia, Cigdem Arikan, Catherine Larson‐Nath, Andréanne N. Zizzo, Thomas Damgaard Sandahl, Christos Tzivinikos, Nehal M. El‐Koofy, Mohamed A. Elmonem, Amal A. Aqul, Wikrom Karnsakul, Pinar Bulut, Nanda Kerkar, Victorien M. Wolters, Amin J. Roberts, Helen M. Evans, Maria Camila Sanchez, Maria Lorena Cavalieri, Deirdre A. Kelly, Jane Hartley, Way Seah Lee, Christina Hajinicolaou, Chatmanee Lertudomphonwanit, Ryan T. Fischer, Jesus Quintero Bernabeu, Ruben E. Quiros‐Tejeira, Cristina Targa Ferreira, Elisa Carvalho, John Eshun, Aglaia Zellos, Antal Dezsőfi, Raquel Borges Pinto, Kathleen Schwarz, Maria Rogalidou, Jennifer Garcia, María Legarda Tamara, Marisa Beretta, Quais Mujawar, Ermelinda Santos‐Silva, Cristina Molera Busoms, Eberhard Lurz, Cristina Gonçalves, Carolina Jimenez‐Rivera, Jesus M. Banales, Richard J. Thompson, Bettina E. Hansen, Binita M. Kamath, The Global ALagille Alliance (GALA) Study Group   +97 more
wiley   +1 more source

Incidence and outcome of biliary atresia in Shanghai, China from 2015 to 2016: a cohort study

BMJ Paediatrics Open
Demographic characteristics and clinical data of all newly diagnosed biliary atresia patients in Shanghai were collected from 1 January 2015 to 31 October 2016.
Gong Chen, Weili Yan, Zhen Shen, Rui Dong, Shan Zheng, Yifan Yang   +5 more
doaj   +1 more source